Identification and Characterization of Genes Related to the Development of Skeletal Muscle in the Hainan Black Goat

文献类型： 外文期刊

第一作者： Xu, Tie Shan

作者： Xu, Tie Shan;Zhou, Han Lin;Rung, Guang;Sun, Wei Ping;Zhang, Xiao Hui;Gu, Li Hong

作者机构：

关键词： Hainan Black goat;skeletal muscle;gene expression;suppression subtractive hybridization

期刊名称：BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY （ 影响因子：2.043； 五年影响因子：2.017 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： In total, 185 unigenes were identified from 380 clones of postnatal skeletal muscle of Hainan Black goats by suppression subtractive hybridization (SSH) technology. Most of the differentially expressed genes involved energy metabolism and muscle contraction. The expression of 19 genes was analyzed in the longissimus dorsi muscles of 2-, 6-, 12-, 24-month olds, and four gene expression patterns were found by hierarchical cluster analysis. Most genes in first expression pattern belonged to myofibrillar proteins and had higher expression levels at 2 months old; genes of the secondary expression pattern had higher expression levels at 12 months old; tropomyoain 1 (alpha) (TPM1) was classified into the third expression pattern, and its expression level showed decreases tendency as age increased. Tropomyoain 2 (beta) (TPM2) was classified into the third expression pattern, which had the opposite expression pattern against TPM1.

分类号： Q

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