Adaptation of Genotype 3 Hepatitis E Virus in Eastern China and Inverse Correlation with Genotype 4 Hepatitis E Virus

文献类型： 外文期刊

第一作者： Si, Fusheng

作者： Si, Fusheng;Yang, Qian;Zhu, Yumin;Dong, Shijuan;Yu, Ruisong;Shen, Shiyuan;Li, Zhen;Zhu, Yumin;Dong, Shijuan;Yu, Ruisong;Shen, Shiyuan;Li, Zhen

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期刊名称：INTERVIROLOGY （ 影响因子：1.763； 五年影响因子：1.929 ）

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收录情况： SCI

摘要： We studied the distribution and development of hepatitis E virus (HEV) genotypes 3 and 4 in pig farms located within the Shanghai metropolitan area. A total of 1,487 swine fecal samples were collected from 39 pig farms during 2009-2010. The average incidence rates for genotype 3 and genotype 4 HEV were 10.6 and 9.3%, respectively. The frequencies of genotype 3 and genotype 4 HEV among the farms were inversely related (r = -0.7423), suggesting that the two genotypes competed within the environmental niche provided by the porcine host. In addition, all of the farms tested positive for both genotype 3 and genotype 4 HEV, indicating that the former is becoming more prevalent in the Shanghai area. The overall HEV incidence rate during 2009-2010 was 20%, which supports the existence of homeostasis within the porcine HEV reservoir

分类号： Q93

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