Surface characteristics and blood compatibility of PVDF/PMMA membranes

文献类型： 外文期刊

第一作者： Ai, Fei

作者： Ai, Fei;Li, Hong;Yuan, Wang Zhang;Chen, Xiaoyong;Yang, Libin;Zhao, Junhong;Zhang, Yongming;Wang, Quan

作者机构：

期刊名称：JOURNAL OF MATERIALS SCIENCE （ 影响因子：4.22； 五年影响因子：3.69 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Poly(vinylidene fluoride) (PVDF)/poly(methyl methacrylate) (PMMA) membranes have important applications as biomaterials. In this study, PVDF/PMMA with varying ratios is blown into membranes, the surface property and blood compatibility of which are thoroughly investigated. Membrane surface characteristics including composition and topography exert considerable influence on the blood compatibility. Introduction of PMMA disturbs PVDF crystallization, however, favors the β phase crystal formation. PVDF content, crystallization ability, and surface enrichment have decisive effects on the membranesurface composition. Meanwhile, with increased PMMA fraction, the membrane surface roughness is also increased,and subsequently results in decreased hemocompatibility. While the membranes with PMMA content lower than30 wt% show good blood compatibility, those with higher PMMA fraction exhibit obvious platelet adhesion to the surface. Thermal annealing promotes the formation of β phase PVDF and generates much smoother surface, thus endowing the membranes with greatly enhanced blood compatibility. These results show the prospect for optimization of processability, surface property, and blood compatibilityof PVDF/PMMA membranes through facile modulation of PMMA content and fabrication process.

分类号： TB3

  • 相关文献
作者其他论文 更多>>

微信小程序