The Epitopes of Foot and Mouth Disease

文献类型： 外文期刊

第一作者： Tang, Hua

作者： Tang, Hua;Liu, Xin Sheng;Fang, Yu Zhen;Pan, Li;Zhang, Zhong Wang;Zhou, Peng;Lv, Jian Liang;Jiang, Shou Tian;Hu, Wen Fa;Zhang, Pan;Wang, Yong Lu;Zhang, Yong Guang

作者机构：

期刊名称：ASIAN JOURNAL OF ANIMAL AND VETERINARY ADVANCES （ 影响因子：0.869； ）

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收录情况： SCI

摘要： In recent years, as the genome sequencing technology and protein peptide chemical synthesis technology become mature, especially the proposal of epitopic biology, more and more Foot-and-mouth Disease Virus (FMDV) antigenic epitopes are revealed. Studies on epitopes have greatly promoted the development of new-type vaccines since the early 1980s. Thanks to the consecutive discovery of new epitopes, people can overcome the Major Histocompatibility Complex (MHC) restriction between species more easily. Researchers could also produce poly-vaccine containing epitopes of different serotypes. The selected epitope sequences are highly conserved in different serotypes and this is the key guarantee of cross immune response of vaccine. It is obvious that epitope will play a key role in elaborating new-type FMDV vaccines. This study summarized the epitopes of FMDV.

分类号： S85

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