文献类型： 外文期刊
第一作者： Liu, Shuai
作者： Liu, Shuai;Wang, Hui;Zuo, Wen-jian;Zhao, You-xing;Li, Xiao-na;Mei, Wen-li;Dai, Hao-fu;Liu, Shuai;Wang, Hui;Zuo, Wen-jian;Zhao, You-xing;Li, Xiao-na;Mei, Wen-li;Dai, Hao-fu;Liu, Shuai
作者机构：
关键词： Aglaia odorata var. microphyllina;Rocaglamide derivatives
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Phytochemical investigation of Aglaia odorata var. microphyllina led to the isolation of two new rocaglamide derivatives and three known ones. The structures of the two new compounds were elucidated as 8b-methoxy-desmethylrocaglamide (1) and 3'-hydroxy-8b-methoxy-rocaglamide (2) by spectroscopic techniques (IR, MS, ID and 2D NMR) and comparing with published data. All the five compounds were evaluated for cytotoxic activity against K562 cell line by MTT method. The results indicated that the OH at 8bposition was a decisive group for cytotoxic activity.
分类号： Q946
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