Analysis of the genetic effects of prolactin gene polymorphisms on chicken egg production

文献类型： 外文期刊

第一作者： Li, Hui-Fang

作者： Li, Hui-Fang;Shu, Jing-Ting;Shan, Yan-Ju;Chen, Kuan-Wei;Zhang, Xue-Yu;Han, Wei;Xu, Wen-Juan;Du, Yu-Feng

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关键词： Prolactin gene;Ligase detection reaction;Polymorphism;Egg production;Chicken

期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）

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收录情况： SCI

摘要： Chicken prolactin (PRL) is a physiological candidate gene for egg production. Variations of T8052C and G8113C in exon 5 of PRL gene may associate with chicken egg production. The objective of the study was to investigate the association of these two single nucleotide polymorphisms in PRL gene with egg production of Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by polymerase chain reaction-ligase detection reaction (PCR-LDR) method. The T8052C and G8113C of PRL were significantly associated with age at first egg (AFE) and total egg number at 300 days of age (EN 300). A significant association was also found between T8052C–G8113C haplotypes and AFE as well as EN300, the H2H3 was the most advantageous diplotype foregg production. We putatively drew the conclusion that these two SNPs in PRL gene as well as their haplotypes could be used as the potential molecular markers for egg production traits in chicken.

分类号： Q7

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