A NEW BENZOPHENONE FROM Dobinea delavayi

文献类型： 外文期刊

第一作者： Cheng, Zhong-Quan

作者： Cheng, Zhong-Quan;Ma, Qing-Yun;Zhao, You-Xing;Cheng, Zhong-Quan;Yang, Dan;Yi, Xin-Hui;Zhou, Jun

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关键词： Dobinea delavayi;benzophenone;dobiniside A

期刊名称：CHEMISTRY OF NATURAL COMPOUNDS （ 影响因子：0.809； 五年影响因子：0.708 ）

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收录情况： SCI

摘要： A new benzophenone sesquiterpene dobiniside A (1), together with two known compounds, 4',6-dihydroxy-2,3',4-trimethoxybenzophenone (2) and mangiferin (3), were isolated from the root of Dobinea delavayi. The structure of the new compound was determined on the basis of spectroscopic analysis, including 1D, 2D NMR, and FAB-MS techniques as well as by comparison of the spectral data with those of related compounds reported in the literatures. Compounds 1-3 were screened for antitumor activity in vitro, and compound 3 was shown to possess anti-tumor activity with IC_(50) value of 7.4 X 10~(-5) μm for A-549.

分类号： O6

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