Enantioselective determination of the insecticide indoxacarb in cucumber and tomato by chiral liquid chromatography-tandem mass spectrometry
文献类型: 外文期刊
第一作者: Dong, Fengshou
作者: Dong, Fengshou;Li, Yuanbo;Chen, Xiu;Zheng, Yongquan;Wang, Huanqing;Xiang, Wensheng;Cheng, Youpu
作者机构:
关键词: cucumber;enantioselective degradation;indoxacarb;LC-MS/MS;tomato
期刊名称:CHIRALITY ( 影响因子:2.437; 五年影响因子:2.204 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: A convenient and precise chiral method was developed and validated for measuring indoxacarb enantiomers in cucumber and tomato using liquid chromatography-tandem mass spectrometry (LC-MS/MS) with a reversed-phase Chiralpak AD-RH column. The target analytes were extracted by acetonitrile and then purified by solid phase extraction (SPE) using NH_2/Carb combined-cartridge. Parameters including the matrix effect, linearity, precision, accuracy, and stability were used. Then the proposed method was successfully applied to investigate the possible enantioselective degradation of rac-indoxacarb in cucumber and tomato under open conditions. The results indicated that the degradation of indoxacarb enantiomers followed first-order kinetics in cucumber and tomato. The half-lives of (+)-S-indoxacarb in cucumber and tomato were 3.0 and 5.9 days, respectively; while the (-)-R-indoxacarb were 7.3 and 12.2 days, respectively. The data of the half-lives showed that (+)-S-indoxacarb was preferentially degraded in cucumber and tomato. Moreover, indoxacarb degraded faster in cucumber than in tomato.
分类号: O641
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