Optimization of Microwave-Assisted Extraction of Flavonoid from Radix Astragali using Response Surface Methodology

文献类型： 外文期刊

第一作者： Mao, Weihua

作者： Mao, Weihua;Han, Lujia;Shi, Bo

作者机构：

关键词： Microwave assisted extraction;response surface methodology;optimization;flavonoid;Radix Astragali

期刊名称：SEPARATION SCIENCE AND TECHNOLOGY （ 影响因子：2.475； 五年影响因子：2.077 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Response surface methodology (RSM) was applied to predict optimum conditions for microwave-assisted extraction (MAE) of flavonoid from Radix Astragali. A central composite design was used to monitor the effect of temperature, extraction time, solvent-to-material ratio, and the ethanol concentration on yield of total flavanoid (TFA). Optimum extraction conditions were predicted as 108.2 deg C, 26.7 min, 23.1 ml/g solvent-to-material ratio and 86.2 percent ethanol. The maximum yield 1.234 +- 0.031 mg/g was close to the yield of Soxhlet and higher than that of ultrasound assisted extraction and heat reflux extraction. MAE was an effective alternative to conventional extraction methods.

分类号： TQ028

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