A new flavanocoumarin from the root of Flemingia philippinensis

文献类型: 外文期刊

第一作者: Fu, Manqin

作者: Fu, Manqin;Fu, Manqin;Huang, Riming;Zhang, Nenling;Su, Zhiwei;Qiu, Samuel X.;Deng, Dun

作者机构:

关键词: Flavanocoumarin;Flemingia philippinensis;Leguminosae

期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.861; 五年影响因子:2.572 )

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收录情况: SCI

摘要: One new flavanocoumarin, flemicoumarin A (1) was isolated from the EtOAc-soluble partition of the root of Flemingia philippinensis, along with three known compounds, namely 4,2′-epoxy-4′,5-dihydroxy-7,5′- dimethoxy-3-phenylcoumarin (2), kaempferol 6-C-glucoside (3) and dracocephaloside (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR, CD and MS data. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Compounds 1-4 exhibited inactivity against MCF-7, A549 and Hep-G2 human cancer cell lines in vitro by MTT colorimetric assay.

分类号: R9

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