Efficient antibacterial agents: A review of the synthesis, biological evaluation and mechanism of pleuromutilin derivatives

文献类型： 外文期刊

第一作者： Shang, Ruofeng

作者： Shang, Ruofeng;Guo, Wenzhu;Liang, Jianping;Wang, Jiatu

作者机构：

关键词： Antibacterial activities;Antibacterial mechanism;Chemical modifications;Pleuromutilin;Resistance mechanism

期刊名称：CURRENT TOPICS IN MEDICINAL CHEMISTRY （ 影响因子：3.295； 五年影响因子：4.008 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Pleuromutilins were discovered as natural-product antibiotics in 1950. The modifications of pleuromutilin lead to the successful development of veterinary medicines such as tiamulin and valnemulin. Retapamulin became the first pleuromutilin approved for use in human skin infections. Recent advances have led to the synthesis of pleuromutilins that combine potent antibacterial activity with favorable pharmaceutical properties, and three new pleuromutilins, BC-3781, BC-3205 and BC-7013, have entered clinical trials. In this review, the key pleuromutilin derivatives, as well as related novel derivatives during 2009-2013, and its antibacterial activities, are presented. Moreover, the antibacterial and resistance mechanism are discussed.

分类号： R9

  • 相关文献

[1]Synthesis and Antibacterial Activity of Novel Pleuromutilin Derivatives. Liu, Huixian,Xiao, Sui,Zhang, Lifang,Wang, Xiaoyang,Xue, Feiqun,Zhang, Depeng,Mu, Shuhua.

[2]Action of Chitosan Against Xanthomonas Pathogenic Bacteria Isolated from Euphorbia pulcherrima. Wang, Yanli,Li, Bin,Tang, Qiaomei,Ibrahim, Muhammad,Li, Hongye,Xie, Guanlin,Wang, Yanli,Sun, Guochang,Li, Liping,Wu, Guoxing. 2012

[3]A new diterpene from the stems of Trigonostemon heterophyllus. Li Yi-Xing. 2014

[4]Extract of Syringa oblata: A new biocontrol agent against tobacco bacterial wilt caused by Ralstonia solanacearum. Bai, Wanming,Kong, Fanyu,Zhang, Chengsheng,Bai, Wanming,Lin, Yong.

[5]Five new eudesmane-type sesquiterpenoids from Chinese agarwood induced by artificial holing. Li, Wei,Cai, Cai-Hong,Guo, Zhi-Kai,Wang, Hao,Zuo, Wen-Jian,Dong, Wen-Hua,Mei, Wen-Li,Dai, Hao-Fu.

[6]Inhibitory Effect of Camptothecin against Rice Bacterial Brown Stripe Pathogen Acidovorax avenae subsp avenae RS-2. Dong, Qiaolin,Cai, Li,Hou, Mingsheng,Luo, Ju,Qiu, Wen,Anjum, Syed Ishtiaq,Li, Bin,Xie, Guanlin,Anjum, Syed Ishtiaq,Sun, Guochang.

[7]Mechanism of action of the tri-hybrid antimicrobial peptide LHP7 from lactoferricin, HP and plectasin on Staphylococcus aureus. Xi, Di,Wang, Xiumin,Teng, Da,Mao, Ruoyu,Zhang, Yong,Wang, Xiaojie,Wang, Jianhua,Xi, Di,Wang, Xiumin,Teng, Da,Mao, Ruoyu,Zhang, Yong,Wang, Xiaojie,Wang, Jianhua,Xi, Di.

[8]Antibacterial activity and mechanism of action of chitosan solutions against apricot fruit rot pathogen Burkholderia seminalis. Lou, Miao-Miao,Zhu, Bo,Muhammad, Ibrahim,Li, Bin,Xie, Guan-Lin,Li, Hong-Ye,Lou, Miao-Miao,Zhu, Bo,Muhammad, Ibrahim,Li, Bin,Xie, Guan-Lin,Li, Hong-Ye,Wang, Yan-Li,Sun, Guo-Chang.

[9]Antibacterial activity and mechanism of the ethanol extracts from Sonchus brachyotus DC.. Li, Xiu-Mei,Liu, Jing,Du, Yong-Kai,Wen, Zhi-Guo,Yang, Pei-Long,Wang, Ji-Tong. 2017

[10]NW-G12, A NOVEL NONCHLORINATED CYCLOHEXAPEPTIDE FROM Streptomyces alboflavus 313. Fan, Lixia,Ji, Zhiqin,Wu, Wenjun,Guo, Zhengyan,Fan, Lixia.

[11]Antioxidant, antibacterial and anti-aging activities of intracellular zinc polysaccharides from Grifola frondosa SH-05. Zhang, Chen,Rong, Chengbo,Zhang, Chen,Gao, Zheng,Zhang, Jianjun,Sun, Xinyi,Jia, Le,Hu, Chunlong.

[12]Molecular characterisation of the broad-spectrum resistance to powdery mildew conferred by the Stpk-V gene from the wild species Haynaldia villosa. Qian, C.,Cui, C.,Wang, X.,Zhou, C.,Hu, P.,Li, M.,Li, R.,Xiao, J.,Wang, X.,Chen, P.,Xing, L.,Cao, A.,Qian, C.. 2017

[13]ALS herbicide resistance mutations in Raphanus raphanistrum: evaluation of pleiotropic effects on vegetative growth and ALS activity. Li, Mei,Yu, Qin,Han, Heping,Vila-Aiub, Martin,Powles, Stephen B.,Li, Mei,Vila-Aiub, Martin.

[14]Molecular cloning of heat shock protein gene HSP90 and effects of abamectin and double-stranded RNA on its expression in Panonychus citri (Trombidiformes: Tetranychidae). Tian, Huixia,Yu, Shijiang,Yue, Jiansu,Ran, Chun,Yang, Juan,Ding, Lili,Liu, Haoqiang,Li, Hongjun,Cong, Lin,Ran, Chun,Liu, Bin,Chen, Fei.

[15]Proteomic Analysis Reveals Resistance Mechanism Against Chlorpyrifos in Frankliniella occidentalis (Thysanoptera: Thripidae). Yan, Dan-Kan,Hu, Min,Tang, Yun-Xia,Fan, Jia-Qin,Yan, Dan-Kan,Hu, Min,Tang, Yun-Xia,Fan, Jia-Qin,Yan, Dan-Kan.

[16]Cloning and characterization of the glutamine synthetase gene from Chinese shrimp Fenneropenaeus chinensis. Lai, Xiao Fang,Kong, Jie,Wang, Qing Yin,Wang, Wei Ji,Meng, Xian Hong,Lai, Xiao Fang,Gao, Huan.

[17]Metabolic resistance in Nilaparvata lugens to etofenprox, a non-ester pyrethroid insecticide. Sun, Huahua,Yang, Baojun,Zhang, Yixi,Liu, Zewen,Yang, Baojun.

[18]Resistance Selection and Characterization of Chlorantraniliprole Resistance in Plutella xylostella (Lepidoptera: Plutellidae). Liu, Xia,Ning, Yu-Bo,Qiao, Kang,Wang, Kai-Yun,Wang, Hong-Yan.

[19]Characterization of imidacloprid resistance in the housefly Musca domestica (Diptera: Muscidae). Wang, Qingmin,Gao, Xiwu,Zhang, Lan. 2012

[20]The Y123H substitution perturbs FvCYP51B function and confers prochloraz resistance in laboratory mutants of Fusarium verticillioides. Chen, F.,Diao, Y.,Liu, X.,Fan, J.,Chen, F.,Cools, H. J.,Kelly, S. L.,Kelly, S. L.. 2014

作者其他论文 更多>>

微信小程序