A New Dolabellane Diterpenoid and a Sesquilignan from Aglaia odorata var. microphyllina
文献类型: 外文期刊
第一作者: Liu, Shuai
作者: Liu, Shuai;Liu, Shou-Bai;Wang, Hui;Guo, Zhi-Kai;Zeng, Yan-Bo;Dong, Wen-Hua;Mei, Wen-Li;Dai, Hao-Fu;Yang, Wei;Liu, Shuai
作者机构:
关键词: Aglaia odorata var. microphyllina;Dolabellane diterpenoid;Sesquilignan.
期刊名称:NATURAL PRODUCT COMMUNICATIONS ( 影响因子:0.986; 五年影响因子:1.068 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: One new diterpenoid, 11α, 12βH-dolabella-4,8(17)-dien-3α,7β,18-triol (1) and one new sesquilignan, 9-methoxy-7′,8′-cis-7″,8″-cis-buddlenol B (2), together with three known compounds, (+)-diasyringaresinol (3), N-methyl-5- hydroxy-?~3-pyrrolin-2-one (4) and marmin (5), have been isolated from Aglaia odorata var. microphyllina. Their structures were determined using 1D and 2D NMR spectroscopy. Compound 1 exhibited cytotoxic activity against the K562 cell line with an IC_(50) value of 12.5 μg/mL.
分类号: N
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