Predicting synergistic toxicity of heavy metals and ionic liquids on photobacterium Q67

文献类型: 外文期刊

第一作者: Ge, Hui-Lin

作者: Ge, Hui-Lin;Liu, Shu-Shen;Ge, Hui-Lin;Su, Bing-Xia;Qin, Li-Tang

作者机构:

关键词: Synergism;Concentration addition;Independent action;ICIM model;Uniform design

期刊名称:JOURNAL OF HAZARDOUS MATERIALS ( 影响因子:10.588; 五年影响因子:10.129 )

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年卷期:

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收录情况: SCI

摘要: Results from three mathematical approaches to predict the toxicity of uniform design mixtures of four heavy metals (HMs) including Cd(Ⅱ), Ni(Ⅱ), Cu(Ⅱ), and Zn(Ⅱ) and six ionic liquids (ILs) were compared to the observed toxicity of these mixtures on Vibrio qinghaiensis sp.-Q67. Single toxicity analysis indicated that the ILs had greater toxicity than the HMs. Combined toxicities of HMs and ILs were found to be synergistic. The combined toxicities were underestimated by concentration addition (CA) and independent action (IA) models. However, the mixture toxicities were effectively predicted by the integrated CA with IA based on multiple linear regression model (ICIM). We propose that ICIM model can serve as a useful tool for predicting the toxicity of interactive mixtures.

分类号: TB1

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