Virus-like particles in picornavirus vaccine development
文献类型: 外文期刊
第一作者: Dong, Hu
作者: Dong, Hu;Guo, Hui-Chen;Sun, Shi-Qi
作者机构:
关键词: Picornavirus;Virus-like particles;Vaccine
期刊名称:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY ( 影响因子:4.813; 五年影响因子:4.697 )
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收录情况: SCI
摘要: Virus-like particles (VLP), which are similar to natural virus particles but do not contain viral genes, have brought about significant breakthroughs in many research fields because of their unique advantages. The ordered repeating epitopes of VLP can induce immunity responses similar to those prompted by natural viral infection; thus, VLP vaccines are regarded as candidate alternatives to whole-virus vaccines. As picornavirus has serious impacts on human and animal health, the development of efficient and safe vaccines is a key endeavor in preventing virus infections. The characteristics of picornavirus capsid proteins allow the development of VLP vaccines. This paper investigates research scenarios and progress on picornavirus VLP vaccines with the aim of providing a reference for researchers focusing on virology and vaccinology.
分类号: Q939.9`Q81
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