Seasonal changes and human chorionic gonadotrophin (hCG) effects on innate immune genes expression in goldfish (Carassius auratus)

文献类型： 外文期刊

第一作者： Zhong, Huan

作者： Zhong, Huan;Zhang, Ming;Zhong, Huan;Zhou, Yi;Xiao, Jun;Gan, Xi;Zhou, Yi;Yu, Fan

作者机构：

关键词： Human chorionic gonadotrophin;Innate immunity;LH;HPG axis;Goldfish

期刊名称：FISH & SHELLFISH IMMUNOLOGY （ 影响因子：4.581； 五年影响因子：4.851 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： We profiled the expression of a group of proinflammatory immune genes, comprising TNF alpha-1, TNF alpha-2, IFN-gamma, IL1 beta-1, IL1 beta-2, CCL-1, and CXCL-8 in liver, head kidney, gills, and spleen of goldfish, during the reproductive cycle and in response to injection of the hormone human chorionic gonadotrophin (hCG). Most genes showed higher expression during the breeding season in both sexes. However, activation of immune responses was much stronger in female goldfish. Injection with hCG, an analog of luteinizing hormone (LH), which is involved in numerous reproductive functions, markedly changed gene expression in most studied organs, in both male and female goldfish. Again, female goldfish were found to be more responsive than male goldfish. The strongest activation of these genes was seen 7 days post-injection; the effect was dose dependent with a lower dose being in general more effective. For several of the genes, the gills were the most responsive tissue and, in male goldfish, gills were often the only responsive tissue, suggesting an important immunological role for gills during breeding. The data suggest that increasing expression levels are regulated by LH arising during the breeding season, with greater sensitivity in female goldfish than in male goldfish. These data support an interaction between the innate immune system and the reproductive axis.

分类号： S9

  • 相关文献

[1]Interaction between neurotrophin 4 and gonadotrophin in bovine oviducts. Sun, Yongfeng,Zhang, Jing,Li, Chunjin,Ma, Yonghe,Sun, Yanling,Liu, Zhuo,Wang, Chunqiang,Zhou, Xu,Sun, Yongfeng,Wang, Dong,Wang, Chunqiang.

[2]Regulation of the two kiss promoters in goldfish (Carassius auratus) by estrogen via different ER alpha pathways. Wang, Qian,Li, Shuisheng,Liu, Xiaochun,Lin, Haoran,Sham, Kathy W. Y.,Cheng, Christopher H. K.,Ogawa, Satoshi,Parhar, Ishwar S.,Wang, Qian,Lin, Haoran. 2013

[3]Peptidoglycan Recognition Protein S2 From Silkworm Integument: Characterization, Microbe-Induced Expression, and Involvement in the Immune-Deficiency Pathway. Yang, Jie,Wang, Xiaonan,Wu, Jinmei,Tang, Shunming,Shen, Zhongyuan,Wu, Jinmei. 2015

[4]Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?. Feng, Min,Zhang, Xiquan,Feng, Min,Zhang, Xiquan,Feng, Min,Zhang, Xiquan. 2016

[5]Effects of three strains of intestinal autochthonous bacteria and their extracellular products on the immune response and disease resistance of common carp, Cyprinus carpio. Chi, Cheng,Jiang, Bing,Yu, Xiao-Bo,Liu, Tian-Qiang,Wang, Gao-Xue,Xia, Lei. 2014

[6]Characterization of the Mx and hepcidin genes in Epinephelus akaara asymptomatic carriers of the nervous necrosis virus. Mao, Ming-Guang,Jiang, Jie-Lan,Wang, Ke-Jian,Lei, Ji-Lin,Lei, Ji-Lin,Mao, Ming-Guang,Lei, Ji-Lin,Peralvarez-Marin, Alex. 2013

[7]The innate immunity of guinea pigs against highly pathogenic avian influenza virus infection. Zhang, Kun,Xu, Wei wei,Zhang, Zhaowei,Liu, Jing,Sun, Weiyang,Sang, Xiaoyu,Ren, Zhiguang,Yu, Zhijun,Li, Yuanguo,Feng, Na,Wang, Tiecheng,Wang, Hualei,Yang, Songtao,Zhao, Yongkun,Gao, Yuwei,Xia, Xianzhu,Zhang, Kun,Li, Jing,Liu, WenJun,Sun, Lijuan,Zhang, Xuemei,Jiao, Peirong,Liao, Ming,Wilker, Peter R.,Chen, Hualan. 2017

[8]Characterization of complement 1q binding protein of tiger shrimp, Penaeus monodon, and its C1q binding activity. Yang, Lishi,Liu, Xianjun,Liu, Wenjing,Li, Xiaolan,Qiu, Lihua,Huang, Jianhua,Jiang, Shigui,Liu, Xianjun,Liu, Wenjing,Li, Xiaolan. 2013

[9]Molecular characterization and expression analysis of interferon-gamma-inducible lysosomal thiol reductase (GILT) gene from pearl oyster Pinctada fucata. Zhang, Dianchang,Pan, Dequan,Cui, Shuge,Su, Tianfeng,Qiu, Lihua,Zhu, Caiyan,Jiang, Shigui,Pan, Dequan,Cui, Shuge. 2010

[10]Identification and expression analysis of goose-type lysozyme in half-smooth tongue sole (Cynoglossus semilaevis). Sha, Zhen-Xia,Wang, Qi-Long,Chen, Song-Lin,Liu, Yang. 2012

[11]cDNA cloning and mRNA expression of a tandem-repeat galectin (PoGal2) from the pearl oyster, Pinctada fucata. Zhang, D. C.,Hu, Y. T.,Guo, H. Y.,Cui, S. G.,Su, T. F.,Jiang, S. G.,Hu, Y. T.,Guo, H. Y.,Jiang, S. G.. 2011

[12]Two myeloid differentiation factor 88 (MyD88) isoforms identified in ducks. Cheng, Yuqiang,Wang, Hengan,Yan, Yaxian,Sun, Jianhe,Ding, Chan.

[13]Transcript Profiling of Toll-Like Receptor mRNAs in Selected Tissues of Mink (Neovison vison). Tong, Mingwei,Yi, Li,Cheng, Yuening,Zhang, Miao,Cao, Zhigang,Wang, Jianke,Zhao, Hang,Lin, Peng,Cheng, Shipeng,Yang, Yong.

[14]A multidomain galectin involved in innate immune response of pearl oyster Pinctada fucata. Zhang, Dianchang,Jiang, Shigui,Hu, Yuting,Cui, Shuge,Guo, Huayang,Wu, Kaichang,Li, Youning,Su, Tianfeng,Hu, Yuting,Guo, Huayang,Cui, Shuge.

[15]Metabolic, immune responses in prawn (Penaeus monodon) exposed to ambient ammonia. Yang, Lishi,Yang, Qibin,Jiang, Shigui,Li, Yong,Zhou, Falin,Li, Tao,Huang, Jianhua.

[16]Isolation and characterization of two novel C-type lectins from the oriental river prawn, Macrobrachium nipponense. Xiu, Yunji,Hou, Libo,Wang, Yinghui,Gu, Wei,Meng, Qingguo,Wang, Wen,Xiu, Yunji,Hou, Libo,Wang, Yinghui,Gu, Wei,Meng, Qingguo,Wang, Wen,Xiu, Yunji,Liu, Xiaoqian.

[17]The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-beta signaling pathway. Li, Dan,Yang, Wenping,Yang, Fan,Liu, Huanan,Zhu, Zixiang,Lian, Kaiqi,Liu, Xiangtao,Zheng, Haixue,Lei, Caoqi,Li, Shu,Shu, Hongbing.

[18]A secreted cystatin from the tick Haemaphysalis longicornis and its distinct expression patterns in relation to innate immunity. Zhou, Jinlin,Ueda, Mami,Umemiya, Rika,Battsetseg, Badgar,Boldbaatar, Damdinsuren,Xuan, Xuenan,Fujisaki, Kozo.

[19]Glycyrrhetinic acid extracted from Glycyrrhiza uralensis Fisch induces the expression of Toll-like receptor 4 in Ana-1 murine macrophages. Li, Li,Miao, Jian-Hua,Xu, Yong-Li,Peng, Li-Na,Qiu, Ya-Feng,Gao, Xiao-Qi,Shi, Zi-Xue,Shao, Dong-Hua,Wei, Jian-Chao,Ma, Zhi-Yong,Zhou, Ying. 2011

[20]Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae. Zou, Feng Ming,Lee, Kwang Sik,Kim, Bo Yeon,Jin, Byung Rae,Zou, Feng Ming,Kim, Hong Ja,Gui, Zhong Zheng,Zhang, Guo Zheng,Guo, Xijie. 2015

作者其他论文 更多>>

微信小程序