A 90-day study of three bruchid-resistant mung bean cultivars in Sprague-Dawley rats

文献类型： 外文期刊

第一作者： Yao, Yang

作者： Yao, Yang;Cheng, Xuzhen;Ren, Guixing

作者机构：

关键词： Mung bean;Bruchid-resistant;90-day subchronic toxicity;Safety assessment

期刊名称：FOOD AND CHEMICAL TOXICOLOGY （ 影响因子：6.023； 五年影响因子：5.844 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Mung bean has been traditionally and widely used as an edible and medicinal plant in the South and Southeast Asia. Bruchid resistance mung bean has more potential in commercial use, but scarcely been evaluated for safety through standard in vivo toxicological studies. In the present study, subchronic oral toxicity studies of bruchid-resistant mung bean were designed and conducted in Sprague-Dawley (SD) rats for 90 days. During the subchronic oral toxicity study, no mortality and toxicologically significant changes in clinical signs, food consumption, opthalmoscopic examination, hematology, clinical biochemistry, macroscopic findings, organ weights and histopathological examination were noted in animal administered diet containing bruchid-resistant mung bean. These results demonstrated that bruchid resistant mung bean is as safe as conventional mung bean. (C) 2014 Elsevier Ltd. All rights reserved.

分类号： R99

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