Molecular and antigenic characteristics of Newcastle disease virus isolates from domestic ducks in China

文献类型： 外文期刊

第一作者： Wu, Wei

作者： Wu, Wei;Liu, Huairan;Zhang, Tingting;Han, Zongxi;Jiang, Yanyu;Xu, Qianqian;Shao, Yuhao;Li, Huixin;Kong, Xiangang;Liu, Shengwang;Wu, Wei;Chen, Hongyan

作者机构：

关键词： Newcastle disease virus;Genomic characteristics;Antigenic relatedness;Pathogenicity;Domestic ducks

期刊名称：INFECTION GENETICS AND EVOLUTION （ 影响因子：3.342； 五年影响因子：3.188 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Newcastle disease (ND) is one of the most devastating diseases to the poultry industry. The causative agents of ND are virulent strains of Newcastle disease virus (NDV), which are members of the genus Avulavirus within the family Paramyxoviridae. Waterfowl, such as ducks and geese, are generally considered potential reservoirs of NDV and may show few or no clinical signs when infected with viruses that are obviously virulent in chickens. However, ND outbreaks in domestic waterfowl have been frequently reported in many countries in the past decade. In this study, 18 NDV strains isolated from domestic ducks in southern and eastern China, between 2005 and 2013, were genetically and phylogenetically characterized. The complete genomes of these strains were sequenced, and they exhibited genome sizes of 15,186 nucleotides (nt), 15,192 nt, and 15,198 nt, which follow the "rule of six" that is required for the replication of NDV strains. Based on the cleavage site of the F protein and pathogenicity tests in chickens, 17 of our NDV isolates were categorized as lentogenic viruses, and one was characterized as a velogenic virus. Phylogenetic analysis based on the partial sequences of the F gene and the complete genome sequences showed that there are at least four genotypes of NDV circulating in domestic ducks; GD1, AH224, and AH209 belong to genotypes VIId, lb, and II of class II NDVs, respectively, and the remaining 15 isolates belong to genotype 1b of class I NDVs. Cross-reactive hemagglutination inhibition tests demonstrated that the antigenic relatedness between NDV strains may be associated with their genotypes, rather than their hosts. These results suggest that though those NDV isolates were from duck, they still don't form a phylogenetic group because they came from the same species; however, they may play an important role in promoting the evolution of NDVs. (C) 2015 Elsevier B.V. All rights reserved.

分类号： R1

  • 相关文献

[1]Genetic, antigenic, and pathogenic characteristics of Newcastle disease viruses isolated from geese in China. Xu, Qianqian,Sun, Junfeng,Gao, Mengying,Zhao, Shasha,Liu, Huairan,Zhang, TingTing,Han, Zongxi,Kong, Xiangang,Liu, Shengwang.

[2]Two single mutations in the fusion protein of Newcastle disease virus confer hemagglutinin-neuraminidase independent fusion promotion and attenuate the pathogenicity in chickens. Ji, Yanhong,Liu, Tao,Jia, Yane,Liu, Bin,Cui, Xiaole,Guo, Fengfeng,Chang, Huiyun,Zhu, Qiyun,Yu, Qingzhong.

[3]Infectivity and Pathogenicity of Newcastle Disease Virus Strains of Different Avian Origin and Different Virulence for Mallard Ducklings. Dai, Yabin,Liu, Mei,Cheng, Xu,Shen, Xinyue,Wei, Yuyong,Zhou, Sheng,Yu, Shengqing,Ding, Chan. 2013

[4]Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011. Wu, Hai-bo,Wu, Nan-ping,Wu, Hai-bo,Guo, Chao-tan,Wo, En-kang,You, Jin-biao,Wang, Yi-ting,Wang, Qiao-gang,Lu, Ru-feng,Xu, Li-hua. 2012

[5]Isolation and characterization of a novel H10N2 avian influenza virus from a domestic duck in Eastern China. Wu, Haibo,Wu, Xiaoxin,Peng, Xiaorong,Cheng, Linfang,Lu, Xiangyun,Jin, Changzhong,Xie, Tiansheng,Yao, Hangping,Wu, Nanping,Lu, Kufeng,Xu, Lihua.

[6]Genomic Characteristics and Changes of Avian Infectious Bronchitis Virus Strain CK/CH/LDL/97I after Serial Passages in Chicken Embryos. Zhao, Fei,Han, Zongxi,Zhang, Tingting,Shao, Yuhao,Kong, Xiangang,Ma, Huijie,Liu, Shengwang.

[7]Host Innate Immune Responses of Ducks Infected with Newcastle Disease Viruses of Different Pathogenicities. Kang, Yinfeng,Li, Yanling,Yuan, Runyu,Feng, Minsha,Xiang, Bin,Sun, Minhua,Li, Yaling,Xie, Peng,Tan, Yangtong,Ren, Tao,Kang, Yinfeng,Li, Yanling,Yuan, Runyu,Feng, Minsha,Xiang, Bin,Sun, Minhua,Li, Yaling,Xie, Peng,Tan, Yangtong,Ren, Tao,Kang, Yinfeng,Li, Yanling,Feng, Minsha,Xiang, Bin,Ren, Tao,Yuan, Runyu,Sun, Minhua. 2015

[8]Chimeric rabies glycoprotein with a transmembrane domain and cytoplasmic tail from Newcastle disease virus fusion protein incorporates into the Newcastle disease virion at reduced levels. Yu, Gui Mei,Zu, Shu Long,Zhou, Wei Wei,Wang, Xi Jun,Shuai, Lei,Wang, Xue Lian,Ge, Jin Ying,Bu, Zhi Gao. 2017

[9]Newcastle disease virus employs macropinocytosis and Rab5a-dependent intracellular trafficking to infect DF-1 cells. Tan, Lei,Zhang, Yuqiang,Zhan, Yuan,Yuan, Yanmei,Sun, Yingjie,Qiu, Xusheng,Meng, Chunchun,Song, Cuiping,Liao, Ying,Ding, Chan,Ding, Chan. 2016

[10]Mitophagy promotes replication of oncolytic Newcastle disease virus by blocking intrinsic apoptosis in lung cancer cells. Meng, Gang,Xia, Mao,Wang, Diancheng,Chen, Aiping,Wang, Hongwei,Yu, Decai,Wei, Jiwu,Yu, Decai,Wei, Jiwu,Wang, Yongshan. 2014

[11]Immune Effect of Newcastle Disease Virus DNA Vaccine with C3d as a Molecular Adjuvant. Zhao, Kai,Duan, Xutong,Hao, Lianwei,Wang, Xiaohua,Zhao, Kai,Duan, Xutong,Wang, Yunfeng. 2017

[12]F gene recombination between genotype II and VII Newcastle disease virus. Sun, Lei,Zhu, Yiping,Kitamura, Yoshihiro,Liu, Wenjun,Qin, Zhuoming,Ma, Baochen,Cui, Zhizhong. 2008

[13]Two myeloid differentiation factor 88 (MyD88) isoforms identified in ducks. Cheng, Yuqiang,Wang, Hengan,Yan, Yaxian,Sun, Jianhe,Ding, Chan.

[14]Recombinant infectious bursal disease virus expressing Newcastle disease virus (NDV) neutralizing epitope confers partial protection against virulent NDV challenge in chickens. Li, Kai,Gao, Li,Gao, Honglei,Qi, Xiaole,Gao, Yulong,Qin, Liting,Wang, Yongqiang,Wang, Xiaomei.

[15]Newcastle disease virus-like particles induce dendritic cell maturation and enhance viral-specific immune response. Qian, Jing,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Xu, Xiaohong,Cong, Yanlong,Ding, Zhuang,Qian, Jing,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Xu, Xiaohong,Cong, Yanlong,Ding, Zhuang,Sun, Yixue,Wang, Jianzhong,Ding, Chan,Yu, Shengqing,Liu, Xiufan,Hu, Shunlin.

[16]Genetic variation in V gene of class II Newcastle disease virus. Hao, Huafang,Liu, Peng,Ren, Shanhui,Gao, Xiaolong,Wang, Yanping,Wang, Xinglong,Zhang, Shixia,Yang, Zengqi,Chen, Shengli.

[17]Proteomic analysis of chicken peripheral blood mononuclear cells after infection by Newcastle disease virus. Deng, Xiaoyu,Cong, Yanlong,Yin, Renfu,Ding, Zhuang,Yang, Guilian,Wang, Chunfeng,Ding, Chan,Yu, Shengqing,Liu, Xiufan,Wang, Chunfeng.

[18]Antiviral activity of rChIFN-alpha against vesicular stomatitis virus and Newcastle disease virus: A novel recombinant chicken interferon-alpha showed high antiviral activity. Hou, Fengxiang,Liu, Ke,Shen, Ting,Zhou, Bin,Cao, Ruibin,Li, Peide,Chen, Puyan,Hou, Fengxiang. 2011

[19]Molecular characterization and expression analysis of the duck viperin gene. Zhong, Zifu,Ji, Yanhong,Fu, Yuguang,Liu, Bin,Zhu, Qiyun.

[20]Recombinant Newcastle disease virus expressing human TRAIL as a potential candidate for hepatoma therapy. Wu, Yunzhou,An, Ying,Yan, Shijun,Yin, Jiechao,Li, Deshan,He, Jinjiao,Geng, Jingshu,Ye, Xianlong,Yu, Qingzhong,Zhang, Zhenyu.

作者其他论文 更多>>

微信小程序