Preventive Effect of Lactobacillus fermentum Zhao on Activated Carbon-Induced Constipation in Mice

文献类型： 外文期刊

第一作者： Zhao, Xin

作者： Zhao, Xin;Qian, Yu;Li, Guijie;Suo, Huayi;Du, Muying;Liu, Zhenhu;Li, Jian

作者机构：

关键词： Lactobacillus fermentum Zhao;activated carbon;constipation;bisacodyl;gastrointestinal transit

期刊名称：JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY （ 影响因子：2.0； 五年影响因子：1.653 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The aim of this study was to investigate the effects of Lactobacillus fermentum Zhao (LF-Zhao) on activated carbon-induced constipation in ICR mice. ICR mice were administered lactic acid bacteria by gavage for 9 d. Body weight, diet intake, drinking amount, stool status, gastrointestinal transit distance and stool time, in addition to motilin (MTL), gastrin (Gas), endothelin (ET), somatostatin (SS), acetylcholinesterase (AChE), substance P (SP) and vasoactive intestinal peptide (VIP) levels in serum were monitored to evaluate the preventive effects of LF-Zhao on constipation. Bisacodyl, a laxative drug, was used as a positive control. Times to the first black stool for normal (untreated), control (no lactic acid bacteria treatment but activated carbon treated), bisacodyl-treated and L. delbrueckii subsp. bulgaricus (LB), LF-Zhao (L) (low concentration of 1x10(8) CFU/mL)- and LF-Zhao (H) (high concentration of 1 x 10(9) CFU/mL)-treated mice induced by activated carbon were 90, 218, 117, 180, 169 and 156 mm, respectively. Following the consumption of LB, LF-Zhao (L) and LF-Zhao (H) or the oral administration of bisacodyl, the gastrointestinal transit distances were reduced by 55.2%, 61.3%, 70.6% and 94.6%, respectively. The serum levels of MTL, Gas, ET, AChE, SP and VIP were significantly increased and the serum levels of SS were reduced in the mice treated with LF-Zhao compared with those in the control mice (p<0.05). These results demonstrated that lactic acid bacteria demonstrate preventive effects on mouse constipation and that LF-Zhao alleviated constipation symptoms better than LB.

分类号： R15

  • 相关文献

[1]Preventive effect of Lactobacillus fermentum Lee on activated carbon-induced constipation in mice. Qian, Yu,Zhao, Xin,Li, Gui-Jie,Suo, Huayi,Du, Muying,Li, Jian,Song, JIa-Li,Liu, Zhenhu. 2015

[2]Therapeutic Effect of Activated Carbon-Induced Constipation Mice with Lactobacillus fermentum Suo on Treatment. Suo, Huayi,Xie, Jie,Zhao, Xin,Qian, Yu,Li, Guijie,Liu, Zhenhu,Li, Jian. 2014

[3]Therapeutic effects of Lactobacillus casei Qian treatment in activated carbon-induced constipated mice. Zhao, Xin,Qian, Yu,Li, Gui-Jie,Suo, Hua-Yi,Liu, Zhen-Hu,Li, Jian.

[4]Laxative effects of partially defatted flaxseed meal on normal and experimental constipated mice. Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Xu, Jiqu,Deng, Qianchun,Huang, Qingde,Yang, Jin'e,Huang, Fenghong,Zhou, Xiaoqi,Yang, Nianhong,Chen, Chang. 2012

[5]Production of Mesoporous Activated Carbon from Tea Fruit Peel Residues and Its Evaluation of Methylene Blue Removal from Aqueous Solutions. Gao, Junjie,Wang, Yuefei,Wu, Jing,Xu, Ping,Kong, Dedong,Sun, Shili. 2013

[6]REMOVAL OF ARSENATE (V) BY SURFACTANT-MODIFIED ACTIVATED CARBON. Zhang, Guangzhi,Sun, Weiling,Zhao, Bin,Lu, Xuemei,Ni, Jinren,Hu, Hao. 2012

[7]Porous carbons from hydrothermal carbonization of corn stover for highly efficient CO2 capture. Qi, Xinhua,Wang, Yu,Shen, Feng. 2017

[8]Adsorption of methylene blue onto activated carbon produced from tea (Camellia sinensis L.) seed shells: kinetics, equilibrium, and thermodynamics studies. Gao, Jun-jie,Zhou, Tao,Xu, Ping,Hochstetter, Danielle,Wang, Yue-fei,Qin, Ye-bo,Cao, Dong-dong,Wang, Yue-fei. 2013

[9]Performance of microbiological control by a point-of-use filter system for drinking water purification. Su Fengyi,Zhang Fei,Li Peng,Xing Xinhui,Luo Mingfang,Lou Kai.

[10]Non-noble metal catalyst for carbon monoxide selective oxidation in excess hydrogen. Jiang, Y,Xie, HM,Qiu, FL. 2005

[11]Porous carbonaceous materials from hydrothermal carbonization and KOH activation of corn stover for highly efficient CO2 capture. Shen, Feng,Wang, Yu,Li, Luyang,Zhang, Keqiang,Qi, Xinhua,Wang, Yu,Li, Luyang,Smith, Richard L.. 2018

[12]Analysis of eight organophosphorus pesticide residues in fresh vegetables retailed in agricultural product markets of Nanjing, China. Wang, Ligang,Jiang, Xin,Wang, Ligang,Liang, Yongchao,Wang, Ligang,Liang, Yongchao. 2008

[13]Adsorption of avermectins on activated carbon: Equilibrium, kinetics, and UV-shielding. Gu Wei,Sun Chang-jian,Liu Qi,Cui Hai-xin. 2009

[14]Preparation of activated carbon from a renewable agricultural residue of pruning mulberry shoot. Wang, Jun,Wu, Fu-An,Wang, Meng,Qiu, Ning,Liang, Yao,Fang, Shui-Qin,Jiang, Xing,Wu, Fu-An. 2010

[15]Co-pyrolysis behaviour and kinetic of two typical solid wastes in China and characterisation of activated carbon prepared from pyrolytic char. Ma, Yuhui,Niu, Ruxuan,Wang, Xiaona,Wang, Qunhui,Wang, Xiaoqiang,Sun, Xiaohong.

作者其他论文 更多>>

微信小程序