Similar regulation of two distinct UL24 promoters by regulatory proteins of equine herpesvirus type 1 (EHV-1)
文献类型: 外文期刊
第一作者: Ma, Yue
作者: Ma, Yue;Liu, Diqiu;Wang, Xiaojun;Gao, Jun;Wang, Xiaojun
作者机构:
关键词: Equine herpesvirus type 1;UL24;Double promoters;Transcriptional regulation;Regulatory protein
期刊名称:FEBS LETTERS ( 影响因子:4.124; 五年影响因子:3.814 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: To characterise the pattern of the transcriptional regulation of equine herpesvirus type 1 (EHV-1) UL24 by regulatory proteins, we identified two distinct promoter regions and two transcription initiation (Tci) sites located upstream of the UL24 open reading frame (ORF). The ORF proximal promoter exhibited higher cis-activity than that of the distal one. Contrary to the former, the latter performed its function dependent on an initiator (INR) due to its lack of a TATA box. Our results showed that the EHV-1 regulatory proteins EICP0, EICP22 and ETIF trans-activated the two promoters, whereas IEP and IR2P displayed negative regulation. In summary, the regulatory proteins exhibited similar regulatory patterns for the two distinct promoters of EHV-1 UL24. (C) 2015 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.
分类号: Q5
- 相关文献
作者其他论文 更多>>
-
Equine lentivirus Gag protein degrades mitochondrial antiviral signaling protein via the E3 ubiquitin ligase Smurf1
作者:Chen, Kewei;Zhou, Bingqian;Wang, Xinhui;Yang, Guangpu;Lin, Yuezhi;Wang, Xuefeng;Du, Cheng;Wang, Xiaojun
关键词:lentivirus; EIAV; HIV; MAVS; RLR
-
Isoglycyrrhizin supplementation of frozen goat semen-extender improves post-thaw sperm quality and in vitro fertilization rates
作者:Liu, Fuqin;Sun, Lingwei;Xu, Jiehuan;He, Mengqian;Wu, Caifeng;Gao, Jun;Dai, Jianjun;Liu, Fuqin;Sun, Lingwei;Xu, Jiehuan;He, Mengqian;Wu, Caifeng;Gao, Jun;Dai, Jianjun;Shen, Haoxing;Zhu, Huibin;Luo, Feng
关键词:Shanghai chongming white goat; Semen cryopreservation; Isoglycyrrhizin (ISL); Antioxidant; Oxidative stress; In vitro fertilization
-
Probiotic Supplementation Improves Lipid Metabolism Disorders and Immune Suppression Induced by High-Fat Diets in Coilia nasus Liver
作者:Gao, Jun;Sun, Yi;Xu, Gangchun;Mang, Qi
关键词:
Coilia nasus ; 4D-DIA proteomics; probiotics supplementation; high-fat diet; lipid metabolism; metabolism disorder -
Microbial-algal symbiotic system drives reconstruction of nitrogen, phosphorus, and methane cycles for purification of pollutants in aquaculture water
作者:Gao, Jun;Mang, Qi;Li, Quanjie;Sun, Yi;Xu, Gangchun;Mang, Qi
关键词:Bacillus subtilis; Chlorella pyrenoidosa; Cross feeding; Environmental microorganisms; Element cycles
-
Characteristics of Intestinal Microbiota and Host Gene Regulation in Coilia nasus Responding to Stress
作者:Gao, Jun;Zhu, Haojun;Gao, Jiancao;Xu, Gangchun
关键词:stress response; intestinal microbiota; oxidative stress; ferroptosis;
Coilia nasus -
Short-Chain Fatty Acids (SCFAs) Modulate the Hepatic Glucose and Lipid Metabolism of Coilia nasus via the FFAR/AMPK Signaling Pathway In Vitro
作者:Gao, Jun;Sun, Yi;Xu, Gangchun;Mang, Qi
关键词:
Coilia nasus ; SCFAs; FFAR/AMPK; high glucose; high lipid -
SlWRKY30, a positive regulator of resistance to Meloidogyne incognita in Solanum lycopersicum
作者:Dang, Yule;Wang, Zhize;Nie, Weidan;Chen, Yinxia;Du, Chong;Li, Yushan;Ma, Yue;Song, Yu;Li, Xiang
关键词:Tomato; SlWRKY; Transcription factor; Root-knot nematode; Signal transduction