Sodium butyrate-induced histone hyperacetylation up-regulating WT1 expression in porcine kidney fibroblasts

文献类型: 外文期刊

第一作者: Tan, Wentao

作者: Tan, Wentao;Wang, Aibing;Chu, Meiran;Shi, Liuxin;Hou, Xiaoxiao;Tang, Bo;Zhang, Xueming;Li, Ziyi;Chen, Yue;An, Peipei

作者机构:

关键词: Histone acetylation;Porcine kidney fibroblasts;Sodium butyrate;Swine;Wilm's tumor 1 gene

期刊名称:BIOTECHNOLOGY LETTERS ( 影响因子:2.461; 五年影响因子:2.457 )

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年卷期:

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收录情况: SCI

摘要: Wilms' tumor 1 gene (WT1) is essential for the development of kidney and histone acetylation and is involved in its expression regulation in mice. However, whether WT1 expression is associated with histone acetylation in porcine kidney cells is unclear. Here, the effect of histone deacetylase inhibitor sodium butyrate (NaBu)-induced hyperacetylation on WT1 expression in porcine kidney fibroblasts (PKF) was examined.

分类号: Q7

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