New Sesquiterpenoids from Ambrosia artemisiifolia L.

文献类型: 外文期刊

第一作者: Huang, Rui

作者: Huang, Rui;Li, Youzhi;Ding, Wenbing;Li, Youzhi;Zhou, Zhongshi

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期刊名称:MOLECULES ( 影响因子:4.411; 五年影响因子:4.587 )

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收录情况: SCI

摘要: A new pseudoguaianolide 1 and two new guaiane-type sesquiterpene glucosides 2 and 3, were isolated from the aerial parts of Ambrosia artemisiifolia L together with two known sesquiterpene dilactones 4 and 5. The new compounds were determined on the basis of spectroscopic and chemical methods to be 3 beta-acetoxy-4 beta-hydroxy-1 alpha,7 alpha, 10 beta,11 alpha H-pseudoguaia-12,8 beta-olide (1), 1 beta,7 beta,9 beta,10 beta,13 alpha H-guaia-4(5)-en-12,6 beta-olide 9-O-beta-d-glucoside (2) and 4 beta-hydroxy-1 alpha,5 alpha,7 alpha,9 alpha H-guaia-10(14),11(13)-dien-12-acid 9-O-beta-d-glucoside (3). The isolated compounds were evaluated for cytotoxicity against human promyelocytic leukemia HL-60 cell lines in vitro, but were all inactive.

分类号: O62

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