Construction and characterization of a recombinant reticuloendotheliosis virus expressing enhanced green fluorescent protein

文献类型: 外文期刊

第一作者: Deng, Xiaoyun

作者: Deng, Xiaoyun;Hua, Yuping;Deng, Xiaoyun;Hu, Feng;Qi, Xiaole;Gao, Li;Li, Kai;Gao, Honglei;Gao, Yulong;Wang, Yongqiang;Shen, Nan;Wang, Xiaomei;Wang, Xiaomei;Deng, Xiaoyun

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期刊名称:ARCHIVES OF VIROLOGY ( 影响因子:2.574; 五年影响因子:2.466 )

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收录情况: SCI

摘要: Reticuloendotheliosis virus (REV) causes an immunosuppressive and oncogenic disease in chickens and other birds. In this study, based on an infectious clone of REV, named HLJR0901, a recombinant virus containing the enhanced green fluorescence protein (EGFP) gene was constructed by inserting the EGFP expression cassette downstream of the 3' terminus of the viral env gene. An EGFP-tagged REV that stably expresses EGFP was rescued. This visible recombinant REV could contribute to the further understanding of the molecular mechanism involved in the replication and pathogenicity of REV.

分类号: R37

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