Antioxidant and antiproliferative activities of polysaccharide fractions from litchi pulp

文献类型： 外文期刊

第一作者： Huang, Fei

作者： Huang, Fei;Zhang, Ruifen;Dong, Lihong;Guo, Jinxin;Deng, Yuanyuan;Zhang, Mingwei;Huang, Fei;Zhang, Ruifen;Dong, Lihong;Yi, Yang

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期刊名称：FOOD & FUNCTION （ 影响因子：5.396； 五年影响因子：5.534 ）

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收录情况： SCI

摘要： Three litchi polysaccharide fractions (LPFs), LP-4, LP-6 and LP-8, were obtained by fractional precipitation using 40%, 60% and 80% ethanol, respectively. The physicochemical properties, chemical antioxidant, and cellular antioxidant and antiproliferative activities of the three polysaccharide fractions were compared. LP-6 contained the highest contents of uronic acid and binding protein among the three fractions, whereas LP-8 contained the least. Amino acid composition analysis of the binding protein revealed that LP-6 contained the most acidic and aromatic amino acids. However, LP-8 contained more galactose and mannose than LP-4 and LP-6. LP-6 exhibited the highest chemical antioxidant activities, with an oxygen radical absorbance capacity of 28.14 mu mol TE per g DW. LP-8 exhibited higher cellular antioxidant activity and a greater inhibitory effect on the proliferation of A549, HepG2 and MGC-803 cells at a concentration of 100-800 mu g mL(-1) than LP-4 and LP-6. In summary, the different LPFs exhibited different antioxidant and antiproliferative activities with differential physicochemical properties.

分类号： TS2

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