Response surface methodology for the enantioseparation of dinotefuran and its chiral metabolite in bee products and environmental samples by supercritical fluid chromatography/tandem mass spectrometry

文献类型： 外文期刊

第一作者： Dong, Fengshou

作者： Dong, Fengshou;Li, Shasha;Xu, Jun;Liu, Xingang;Zheng, Yongquan;Zheng, Zuntao;Xu, Yongwei

作者机构：

关键词： Dinotefuran;Metabolite;Chiral separation;Central composite design;Supercritical fluid chromatography/tandem mass spectrometry

期刊名称：JOURNAL OF CHROMATOGRAPHY A （ 影响因子：4.759； 五年影响因子：4.302 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Tracing the enantiomers of dinotefuran and its metabolite in bee products and relevant environmental matrices is vital because of the high toxicity of their racemates to bees. In this study, a statistical optimization strategy using three-dimensional response surface methodology for the enantioseparation of dinotefuran and its metabolite UF was developed by a novel supercritical fluid chromatography/tandem mass spectrometry (SFC-MS/MS) technique. After direct evaluation of the chromatographic variables - co-solvent content, mobile phase flow rate, automated backpressure regulator pressure (ABPR), and column temperature - involved in the separation mechanism and assessment of the interactions among these variables, the optimal SFC-MS/MS working conditions were selected as a CO2/2% formic acid-methanol mobile phase, 1.9 mL/min flow rate, 2009.8 psi ABPR, and 26.0 degrees C column temperature using an amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase under electrospray ionization positive mode. Baseline resolution, favorable retention, and high sensitivity of the two pairs of enantiomers were achieved in pollen, honey, water, and soil matrices within 4.5 min. Additionally, the parameters affecting the dispersive solid-phase extraction procedure, such as the type and content of extractant or purification sorbents, were systematically screened to obtain better extraction yields of the enantiomers. Mean recoveries were between 78.3% and 100.2% with relative standard deviations lower than 8.0% in all matrices. The limits of quantification ranged from 1.0 mu g/kg to 12.5 mu g/kg for the dinotefuran and UF enantiomers. Furthermore, the developed method was effectively applied to authentic samples from a market, an irrigation canal, and a trial field, and the enantioselective dissipation of, dinotefuran and UF in soil was demonstrated. (C) 2015 Elsevier B.V. All rights reserved.

分类号： O65

  • 相关文献

[1]Headspace solid-phase microextraction-gas chromatography-mass spectrometry analysis of the volatile components of longan (Dimocarpus longan Lour.). Zhang, Yi,Gao, Bei,Zhang, Mingwei,Zhang, Yi,Gao, Bei,Zhang, Mingwei,Xu, Yujuan,Shi, John. 2009

[2]A novel Ganoderma lucidum G0119 fermentation strategy for enhanced triterpenes production by statistical process optimization and addition of oleic acid. Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung,Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung,Feng, Jie,Zhang, Jing-Song,Feng, Na,Yan, Meng-Qiu,Yang, Yan,Jia, Wei,Lin, Chi-Chung.

[3]Optimization of ultrasound-assisted magnetic retrieval-linked ionic liquid dispersive liquid-liquid microextraction for the determination of cadmium and lead in water samples by graphite furnace atomic absorption spectrometry. Wang, Xie,Liu, Haitao,Lin, Chaowen,Pang, Liangyu,Yang, Junwei,Zeng, Qingbin.

[4]Enhancement of botrallin and TMC-264 production in liquid culture of endophytic fungus Hyalodendriella sp Ponipodef12 after treatments with metal ions. Luo, Haiyu,Xu, Dan,Xie, Rushan,Zhang, Xuping,Wang, Jian,Dong, Xuejiao,Lai, Daowan,Zhou, Ligang,Liu, Yang. 2016

[5]Influences of dietary lipid and temperature on growth, fat deposition and lipoprotein lipase expression in darkbarbel catfish (Pelteobagrus vachellii). Qiang, Jun,He, Jie,Li, Hong-Xia,Xu, Pao,Sun, Yi-Lan,Qiang, Jun,Tao, Yi-Fan,Bao, Jin-Wen,Shi, Wen-bo,Xu, Pao. 2017

[6]Stereoselective Determination of a Novel Chiral Insecticide, Sulfoxaflor, in Brown Rice, Cucumber and Apple by Normal-Phase High-Performance Liquid Chromatography. Dong, Fengshou,Xu, Jun,Liu, Xingang,Cheng, Youpu,Liu, Na,Tao, Yan,Zheng, Yongquan.

[7]Stereoselective Determination of Tebuconazole in Water and Zebrafish by Supercritical Fluid Chromatography Tandem Mass Spectrometry. Liu, Na,Dong, Fengshou,Xu, Jun,Liu, Xingang,Chen, Zenglong,Tao, Yan,Pan, Xinglu,Chen, XiXi,Zheng, Yongquan.

[8]Chiral separation of mandelic acid enantiomers using an aqueous two-phase system based on a thermo-sensitive polymer and dextran. Tan, Zhijian,Li, Fenfang,Zhao, Congcong,Teng, Yubin,Liu, Yanfei,Tan, Zhijian,Tan, Zhijian.

[9]Enantioseparation of mandelic acid and alpha-cyclohexylmandelic acid using an alcohol/salt-based aqueous two-phase system. Li, Fen-Fang,Tan, Zhi-Jian,Guo, Zhi-Feng,Tan, Zhi-Jian.

[10]Green synthesis of a typical chiral stationary phase of cellulose-tris(3,5-dimethylphenylcarbamate). Bai, Lian-yang,Liu, Run-Qiang,Zhang, Yi-Jun,Zhang, Yu-Ping,Bai, Lian-yang. 2013

[11]HPLC-MS/MS enantioseparation of triazole fungicides using polysaccharide-based stationary phases. Zhang, Hu,Wang, Minghua,Zhang, Hu,Wang, Minghua,Zhang, Hu,Qian, Mingrong,Wang, Xinquan,Wang, Xiangyun,Xu, Hao,Wang, Qiang,Zhang, Hu,Qian, Mingrong,Wang, Xinquan,Wang, Xiangyun,Xu, Hao,Wang, Qiang,Zhang, Hu,Qian, Mingrong,Wang, Xinquan,Wang, Xiangyun,Xu, Hao,Wang, Qiang.

[12]Characterisation of Neonicotinoid and Pymetrozine Resistance in Strains of Bemisia tabaci (Hemiptera: Aleyrodidae) from China. Rao Qiong,Luo Chen,Rao Qiong,Zhang Hong-yu,Jones, Christopher M.,Devine, Greg J.,Gorman, Kevin,Denholm, Ian,Xu Yong-hua. 2012

[13]Lethal and sublethal effects of dinotefuran on two invasive whiteflies, Bemisia tabaci (Hemiptera: Aleyrodidae). Qu, Cheng,Zhang, Wei,Li, Fengqi,Luo, Chen,Wang, Ran,Tetreau, Guillaume. 2017

[14]Rapid and Sensitive Determination of Dinotefuran Residue Based on Electrochemical Enhancement of beta-cyclodextrin-Graphene Composite. Zhang, M.,Zhai, X. C.,Yang, X.,Zhao, H. T.,Dong, A. J.,Zhang, H.,Wang, J.,Liu, G. Y.,Zhang, M.,Wang, J..

[15]Enantioselective separation and determination of the dinotefuran enantiomers in rice, tomato and apple by HPLC. Dong, Fengshou,Liu, Xingang,Xu, Jun,Li, Jing,Li, Yuanbo,Zheng, Yongquan,Wang, Yunhao.

[16]Enantioselective Degradation of Chiral Insecticide Dinotefuran in Greenhouse Cucumber and Soil. Dong, Fengshou,Xu, Jun,Liu, Xingang,Wang, Yunhao,Zheng, Yongquan,Chen, Xiu.

[17]Residue behaviors and dietary risk assessment of dinotefuran and its metabolites in Oryza sativa by a new HPLC-MS/MS method. Li, Ruijuan,Liu, Tongjin,Zhang, Sicong,Yu, Jianlei,Song, Guochun,Cui, Shuhua.

[18]Metabolomics Investigation of an Association of Induced Features and Corresponding Fungus during the Co-culture of Trametes versicolor and Ganoderma applanatum. Xu, Xiao-Yan,Shen, Xiao-Ting,Yuan, Xiao-Jie,Zhu, Li-Ping,Yang, Song,Zhou, Yuan-Ming,Fan, Huan,Du, Feng-Yu,Sadilek, Martin,Yang, Jie,Qiao, Bin,Yang, Song. 2018

[19]Cytotoxicity and genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic acid (MQCA) in human hepatocytes. Zhang, Keyu,Ban, Manman,Zheng, Haihong,Wang, Xiaoyang,Wang, Mi,Fei, Chenzhong,Xue, Feiqun,Zhao, Zhanzhong. 2012

[20]Determination of Mesotrione and Its Metabolite Residues in Maize by Ultra Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. Deng Li-Gang,Lu Fu-Sui,Deng Li-Gang,Li Zeng-Mei,Zhao Shan-Cang,Chen Ye-Bing,Guo Chang-Ying,Deng Li-Gang,Li Zeng-Mei,Zhao Shan-Cang,Chen Ye-Bing,Guo Chang-Ying. 2013

作者其他论文 更多>>

微信小程序