The role of noncoding regions of classical swine fever virus C-strain in its adaptation to the rabbit

文献类型： 外文期刊

第一作者： Li, Chao

作者： Li, Chao;Li, Yongfeng;Shen, Liang;Huang, Junhua;Sun, Yuan;Luo, Yuzi;Zhao, Bibo;Wang, Chunhua;Yuan, Jin;Qiu, Hua-Ji

作者机构：

关键词： Classical swine fever virus;C-strain;Noncoding regions;Adaptation to the rabbit;Fever induction;Replication in the spleen

期刊名称：VIRUS RESEARCH （ 影响因子：3.303； 五年影响因子：3.445 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Classical swine fever (CSF) is a devastating disease of swine caused by classical swine fever virus (CSFV). C-strain, a modified live vaccine against CSF, was developed through hundreds of passages of a highly virulent CSFV in the rabbit in China in the mid-1950s. To identify the role of noncoding regions (NCRs) of C-strain in its adaptation to the rabbit, we generated and evaluated a series of chimeric viruses derived from C-strain and the highly virulent Shimen strain. The results demonstrated that the NCRs of the C-strain were essential for its fever induction in rabbits and the coding region but not NCRs was necessary for its replication in the spleen of rabbits. (c) 2014 Elsevier B.V. All rights reserved.

分类号： R37

  • 相关文献

[1]Secreted Expression of the Cap Gene of Porcine Circovirus Type 2 in Classical Swine Fever Virus C-Strain: Potential of C-Strain Used as a Vaccine Vector. Zhang, Lingkai,Li, Yongfeng,Xie, Libao,Wang, Xiao,Sun, Yuan,Qiu, Hua-Ji,Gao, Xulei. 2017

[2]Genome and Molecular Characterization of a CSFV Strain Isolated from a CSF Outbreak in South China. Shen, Hai-Yan,Wang, Jia-Ying,Dong, Xiao-Ying,Zhao, Ming-Qiu,Kang, Yanmei,Li, Yin-Guang,Pei, Jing-Jing,Liao, Ming,Ju, Chun-Mei,Yi, Lin,Hu, Yongming,Chen, Jin-Ding,Shen, Hai-Yan. 2013

[3]In vitro inhibition of the replication of classical swine fever virus by capsid-targeted virus inactivation. Wang, Yu-Fei,Wang, Zhong-Hua,Li, Yan,Zhang, Xing-Juan,Sun, Yuan,Li, Miao,Qiu, Hua-Ji. 2010

[4]Identification of host cell binding peptide from an overlapping peptide library for inhibition of classical swine fever virus infection. Li, Xuewu,Wang, Li,Zhao, Dong,Zhang, Gaiping,Luo, Jun,Deng, Ruiguang,Yang, Yanyan. 2011

[5]The protective immune response induced by B cell epitope of classical swine fever virus glycoprotein E2. Liu, SG,Tu, CC,Wang, CL,Yu, XL,Wu, JM,Guo, SP,Shao, ML,Gong, Q,Zhu, QH,Kong, XG. 2006

[6]Generation of a Recombinant Baculovirus Expressing The E2 Protein of Classical Swine Fever Virus and Its Immunogenicity in a Mouse Model. Miao, Li,Wang, Yu-Fei,Yu, Wang,Hui, Gao,Na, Li,Yuan, Sun,Liang, Bing-Bing,Qiu, Hua-Ji. 2009

[7]A multiplex nested RT-PCR for the detection and differentiation of wild-type viruses from C-strain vaccine of classical swine fever virus. Li, Yan,Zhao, Jian-Jun,Li, Na,Shi, Zixue,Cheng, Dan,Zhu, Qing-Hu,Tu, Changchun,Tong, Guang-Zhi,Qiu, Hua-Ji. 2007

[8]RNA interference screening of interferon-stimulated genes with antiviral activities against classical swine fever virus using a reporter virus. Wang, Xiao,Li, Yongfeng,Li, Lian-Feng,Shen, Liang,Zhang, Lingkai,Yu, Jiahui,Luo, Yuzi,Sun, Yuan,Li, Su,Qiu, Hua-Ji.

[9]Specific ligands for classical swine fever virus screened from landscape phage display library. Yin, Long,Luo, Yuzi,Du, Min,Qiu, Hua-Ji,Yin, Long,Liang, Bo,Wang, Fei,Liu, Aihua,Yin, Long,Wang, Fei,Liu, Aihua,Petrenko, Valery A..

[10]Development and evaluation of rapid detection of classical swine fever virus by reverse transcription loop-mediated isothermal amplification (RT-LAMP). Yin, Shuanghui,Shang, Youjun,Zhou, Guangqing,Tian, Hong,Liu, Yanhong,Cai, Xuepeng,Liu, Xiangtao.

[11]Development of a triplex TaqMan real-time RT-PCR assay for differential detection of wild-type and HCLV vaccine strains of classical swine fever virus and bovine viral diarrhea virus 1. Zhang, Xing-Juan,Han, Qiu-Ying,Sun, Yuan,Zhang, Xin,Qiu, Hua-Ji.

[12]Pre-Clinical Evaluation of a Real-Time PCR Assay on a Portable Instrument as a Possible Field Diagnostic Tool: Experiences from the Testing of Clinical Samples for African and Classical Swine Fever Viruses. Liu, L.,Stahl, K.,Belak, S.,Liu, L.,Stahl, K.,Belak, S.,Liu, L.,Luo, Y.,Qiu, H. -J.,Luo, Y.,Qiu, H. -J.,Accensi, F.,Ganges, L.,Rodriguez, F.,Accensi, F.,Rodriguez, F.,Shan, H.,Belak, S..

[13]Efficacy evaluation of the C-strain-based vaccines against the subgenotype 2.1d classical swine fever virus emerging in China. Luo, Yuzi,Ji, Shengwei,Lei, Jian-Lin,Xian, Guang-Tao,Liu, Yan,Gao, Yao,Meng, Xing-Yu,Zheng, Guanglai,Zhang, En-Yu,Wang, Yimin,Du, Ming-Liang,Li, Yongfeng,Li, Su,He, Xi-Jun,Sun, Yuan,Qiu, Hua-Ji.

[14]Enhanced immunity against classical swine fever in pigs induced by prime-boost immunization using an alphavirus replicon-vectored DNA vaccine and a recombinant adenovirus. Sun, Yuan,Li, Na,Li, Hong-Yu,Li, Miao,Qiu, Hua-Ji. 2010

[15]eEF1A Interacts with the NS5A Protein and Inhibits the Growth of Classical Swine Fever Virus. Li, Su,Feng, Shuo,Wang, Jing-Han,He, Wen-Rui,Qin, Hua-Yang,Dong, Hong,Li, Lian-Feng,Yu, Shao-Xiong,Li, Yongfeng,Qiu, Hua-Ji. 2015

[16]Comparison of the protective efficacy of recombinant adenoviruses against classical swine fever. Sun, Yuan,Li, Hong-Yu,Zhang, Xing-Juan,Chang, Tian-Ming,He, Fan,Wang, Xiang-Peng,Liu, Da-Fei,Qiu, Hua-Ji. 2011

[17]Development of a loop-mediated isothermal amplification for visual detection of the HCLV vaccine against classical swine fever in China. Zhang, Xing-Juan,Han, Qiu-Ying,Sun, Yuan,Qiu, Hua-Ji,Belak, Sandor,Liu, Lihong,Belak, Sandor,Liu, Lihong. 2011

[18]Genetic Typing of Classical Swine Fever Virus Isolates from China. Sun, S. -Q.,Yin, S. -H.,Guo, H. -C.,Jin, Y.,Shang, Y. -J.,Liu, X. -T.. 2013

[19]The double-antigen ELISA concept for early detection of E-rns-specific classical swine fever virus antibodies and application as an accompanying test for differentiation of infected from marker vaccinated animals. Meyer, D.,Becher, P.,Postel, A.,Fritsche, S.,Engemann, C.,Luo, Y.,Qiu, H. -J.,Blome, S.,Beyerbach, M.,Chang, C. -Y.. 2017

[20]Experimental infection of Bama miniature pigs with a highly virulent classical swine fever virus. Sun, Yuan,Jiang, Qian,Tian, Da-Yong,Lin, Huan,Li, Hong,Han, Qiu-Ying,Han, Wen,Si, Chang-De,Hu, Shou-Ping,Zhang, Zhuo,Qu, Lian-Dong,Qiu, Hua-Ji. 2011

作者其他论文 更多>>

微信小程序