Balance between metallothionein and metal response element binding transcription factor 1 is mediated by zinc ions

文献类型： 外文期刊

第一作者： Dong, Gang

作者： Dong, Gang;Chen, Hong;Dou, Ye;Wang, Qinglu;Qi, Meiyu

作者机构：

关键词： metallothionein;metal response element-binding transcription factor-1;Zn2+;metal ion metabolism

期刊名称：MOLECULAR MEDICINE REPORTS （ 影响因子：2.952； 五年影响因子：2.754 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Metal ion homeostasis and heavy metal detoxification systems are regulated by certain genes associated with metal ion transport. Metallothionein (MT) and metal response element binding transcription factor 1 (MTF-1) are important regulatory proteins involved in the mediation of intracellular metal ion balance. Differences in the zinc-binding affinities of the zinc fingers of MTF-1 and the alpha- and beta-domains of MT facilitate their regulation of Zn2+ concentration. Alterations in the intracellular concentration of Zn2+ influence the MTF-1 zinc finger number, and MTF-1 containing certain zinc finger numbers regulates the expression of corresponding target genes. The present review evaluates the association between zinc finger number in MTF-1 protein, MTF-1 target genes and the mechanism underlying. MT regulation of the zinc finger number in MTF-1.

分类号： R3

  • 相关文献

[1]Characterization of a Type 1 Metallothionein Gene from the Stresses-Tolerant Plant Ziziphus jujuba. Yang, Mingxia,Cao, Qiufen,Chen, Mingchang,Yang, Mingxia,Dong, Zhigang,Zhang, Fan,Wang, Fan,Cao, Qiufen,Chen, Mingchang. 2015

[2]Effects of water-borne copper on the survival, antioxidant status, metallothionein-I mRNA expression and physiological responses of the Chinese mitten crab, Eriocheir sinensis (Decapoda: Brachyura) larvae. Sun, Shengming,Ge, Xianping,Zhu, Jian,Fu, Hongtuo,Sun, Shengming,Jiang, Zhiqiang. 2014

[3]Survival of Human Metallothionein-2 Transplastomic Chlamydomonas reinhardtii to Ultraviolet B Exposure. Zhang, YK,Shen, GF,Ru, BG.

[4]Overexpression of Iris. lactea var. chinensis metallothionein IIMT2a enhances cadmium tolerance in Arabidopsis thaliana. Gu, Chun-Sun,Zhao, Yan-Hai,Huang, Su-Zhen,Gu, Chun-Sun,Zhao, Yan-Hai,Huang, Su-Zhen,Liu, Liang-qin,Zhu, Xu-dong,Deng, Yan-ming. 2014

[5]Type 1 metallothionein (ZjMT) is responsible for heavy metal tolerance in Ziziphus jujuba. Li, Lan-Song,Liu, Xu-Guang,Li, Lan-Song,Meng, Yu-Ping,Cao, Qiu-Fen,Wang, Fan,Wu, Shu-Biao,Cao, Qiu-Fen,Yang, Yong-Zhen,Jia, Hu-Sheng,Liu, Xu-Guang,Wu, Shu-Biao.

[6]Cloning of metallothionein genes from Arachis hypogaea and characterization of AhMT2a. Quan, X. Q.,Shan, L.,Bi, Y. P..

[7]Cucumber Metallothionein-Like 2 (CsMTL2) Exhibits Metal-Binding Properties. Pan, Yu,Pan, Yanglu,Zhai, Junpeng,Li, Jinhua,Du, Xiaobing,Su, Chenggang,Zhang, Xingguo,Zhai, Junpeng,Xiong, Yan. 2016

[8]Organic zinc absorption by the intestine of broilers in vivo. Yu, Yu,Lu, Lin,Li, Su-Fen,Zhang, Li-Yang,Luo, Xu-Gang,Yu, Yu,Li, Su-Fen. 2017

[9]Total and subcellular distribution of trace elements in the liver of a mother-fetus pair of Dall's porpoises (Phocoenoides dalli). Yang, J,Kunito, T,Anan, Y,Tanabe, S,Miyazaki, N. 2004

[10]HbMT2, an ethephon-induced metallothionein gene from Hevea brasiliensis responds to H2O2 stress. Zhu, Jiahong,Zhang, Quanqi,Wu, Rui,Zhang, Zhili,Zhang, Zhili. 2010

[11]Overexpression of Nelumbo nucifera metallothioneins 2a and 3 enhances seed germination vigor in Arabidopsis. Zhou, Yuliang,Chu, Pu,Chen, Huhui,Li, Yin,Huang, Shangzhi,Liu, Jun,Ding, Yu,Jiang, Liwen,Tsang, Edward W. T.,Wu, Keqiang.

[12]Subcellular distribution of trace elements in kidney of a mother-fetus pair of Dall's porpoises (Phocoenoides dalli). Yang, Jian,Yang, Jian,Miyazaki, Nobuyuki,Kunito, Takashi,Anan, Yasumi,Tanabe, Shinsuke.

[13]The Heterologous Expression of the Iris lactea var. chinensis Type 2 Metallothionein IlMT2b Gene Enhances Copper Tolerance in Arabidopsis thaliana. Gu, Chun-Sun,Huang, Su-Zhen,Lu, Xiao-Qing,Gu, Chun-Sun,Huang, Su-Zhen,Lu, Xiao-Qing,Liu, Liang-Qin,Zhu, Xu-Dong,Deng, Yan-Ming.

[14]Influence of montmorillonite on cadmium accumulation in carp, Carassius auratus. Kim, Song-Gwan,Du, Hua-Hua,Dai, Wei,Xu, Zi-Rong,Kim, Song-Gwan,Dai, Wei,Zhang, Xiao-Feng.

[15]Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures. Zhu, Yongwen,Liao, Xiudong,Lu, Lin,Zhang, Liyang,Luo, Xugang,Zhu, Yongwen,Zhu, Yongwen,Li, Wenxiang,Ji, Cheng,Lin, Xi,Liu, Hsiao-Ching,Odle, Jack. 2017

[16]THE METALLOTHIONEIN GENE FROM THE ORIENTAL RIVER PRAWN MACROBRACHIUM NIPPONENSE (DE HAAN, 1849): CHARACTERIZATION AND EXPRESSION IN RESPONSE TO HYPDXIA AND REOXYGENATION. Sun, Shengming,Gu, Zhimin,Fu, Hongtuo,Zhu, Jian.

[17]Cloning and characterization of HbMT2a, a metallothionein gene from Hevea brasiliensis Muell. Arg differently responds to abiotic stress and heavy metals. Li, Yan,Chen, Yue Yi,Yang, Shu Guang,Tian, Wei Min.

作者其他论文 更多>>
  • Adsorption effect and mechanism of Cd(II) by different phosphorus-enriched biochars

    作者：Zeng, Yang;Lin, Yuhan;Ma, Ming;Chen, Hong;Ma, Ming;Chen, Hong;Ma, Ming;Chen, Hong

    关键词：Phosphorous-enriched biochar; Agricultural and forestry waste; Low-grade phosphate rock and derivatives; Cadmium; Adsorption mechanism; Mineral precipitation

  • Zearalenone Decreases Food Intake by Disrupting the Gut-Liver-Hypothalamus Axis Signaling via Bile Acids

    作者：Yuan, Peiqiang;Ma, Rongman;Huang, Jiancai;Wen, Hongmei;Huang, Lingjie;Li, Hua;Feng, Bin;Zhang, Xiaoling;Lin, Yan;Xu, Shengyu;Li, Jian;Zhuo, Yong;Hua, Lun;Che, Lianqiang;Wu, De;Fang, Zhengfeng;Yuan, Peiqiang;Hu, Liang;Li, Ran;Huang, Lingjie;Chen, Hong;Liu, Yuntao;Fang, Zhengfeng;Wang, Peng;Lin, Sen

    关键词：zearalenone; bile acid metabolism; toxicity; farnesoid X receptor; food intake

  • Spatiotemporal patterns and driving factors of gross primary productivity over the Mongolian Plateau steppe in the past 20 years

    作者：Ding, Lei;Shi, Zhou;Chang, Jinfeng;Li, Zhenwang;Li, Zhenwang;Ding, Lei;Wang, Xu;Shen, Beibei;Shao, Changliang;Xiao, Liujun;Dong, Gang;Yu, Lu;Yu, Lu;Nandintsetseg, Banzragch;Nandintsetseg, Banzragch

    关键词：Gross primary productivity; Mongolian Plateau; Grassland; Climatic factors; Human activity

  • Soil environmental anomalies dominate the responses of net ecosystem productivity to heatwaves in three Mongolian grasslands

    作者：Qu, Lu-Ping;Dong, Gang;Chen, Jingyan;Legesse, Tsegaye Gemechu;Xin, Xiaoping;Shao, Changliang;Chen, Jiquan;Xiao, Jingfeng;De Boeck, Hans J.;De Boeck, Hans J.;Dong, Gang;Jiang, Shicheng;Batkhishig, Ochirbat

    关键词：Climatic extremes; Heat wave; Eurasian; Carbon budget; Steppe; Net ecosystem CO2 exchange

  • Climate-shaped vegetation dominated the spatial pattern of the Bowen ratio over terrestrial ecosystems in China

    作者：Sun, Mingyu;Han, Lang;Yao, Yuan;Wang, Jilong;Yu, Guirui;Chen, Zhi;Hao, Tianxiang;Yang, Meng;Zhang, Weikang;Liu, Zhaogang;Ma, Lexin;Dou, Xiaojun;Luo, Wenxing;Lin, Yong;He, Yongtao;Shi, Peili;Wang, Huimin;Zhang, Yangjian;Zhao, Fenghua;Zhu, Zhilin;Yu, Guirui;Chen, Zhi;Liu, Zhaogang;Ma, Lexin;Dou, Xiaojun;Luo, Wenxing;Lin, Yong;He, Yongtao;Shi, Peili;Zhang, Yangjian;Chen, Zhi;Zhu, Xianjin;Han, Lang;Chen, Shiping;Deng, Zhengmiao;Duh, Hu;Wei, Wenxue;Dong, Gang;Gao, Yanhong;Ji, Xibin;Li, Yuqiang;Tan, Junlei;Gu, Fengxue;Hao, Xiangxiang;Hao, Yanbin;Hen, Qihua;He, Jinsheng;He, Jinsheng;He, Jinsheng;He, Jinsheng;Chen, Shiping;Jiang, Zhengde;Wu, Jiabing;Zhu, Jiaojun;Li, Xinhu;Li, Yingnian;Zhao, Liang;Li, Yuzhe;Zhang, Fawei;Liu, Shaomin;Luo, Weijun;Mo, Xingguo;Zhang, Yiping;Sha, Liqing;Song, Qinghai;Zhang, Yiping;Sun, Dan;Yan, Junhua;Tan, Junlei;Tang, Yakun;Wang, Fei;Wang, Jianlin;Wu, Zhixiang;Xin, Xiaoping;Xin, Xiaoping;Zhang, Yucui;Zhou, Li;Zhang, Weikang;Chen, Zhi

    关键词：Bowen ratio; Heat flux; Sensible heat; Eddy covariance; Spatial patterns; Energy partitioning

  • Bovine enhancer-regulated circSGCB acts as a ceRNA to regulate skeletal muscle development via enhancing KLF3 expression

    作者：Xu, Jiawei;Wen, Yifan;Li, Xinmiao;Yang, Peng;Chen, Ningbo;Lei, Chuzhao;Chen, Hong;Huang, Yongzhen;Peng, Wei;Zhang, Jun;Zhang, Zijing;Wang, Eryao;Liu, Xian;Huang, Yongzhen

    关键词：circSGCB; ceRNA mechanism; Enhancer; KLF3; Muscle development

  • Error Risk Minimization

    作者：Chen, Hong;Zhang, Xuelin;Chen, Hong;Zhang, Xuelin;Gong, Tieliang;Gu, Bin;Zheng, Feng;Chen, Hong;Chen, Hong;Zhang, Xuelin;Gong, Tieliang;Gu, Bin;Zheng, Feng;Gong, Tieliang;Gu, Bin;Zheng, Feng

    关键词：Error density; Robust estimation; Kernel regression; Empirical risk minimization

微信小程序