Simultaneous determination of residues of dipyrone metabolites in goat tissues by hydrophilic interaction liquid chromatography tandem mass spectrometry
文献类型: 外文期刊
第一作者: Zhang, Chong
作者: Zhang, Chong;Zhang, Lifang;Jiang, Zhaoling;Zhang, Xiaoxiao;Xue, Feiqun;Zhang, Chong;Cao, Suqing;Wu, Hao;Yan, Ming;Jiang, Shanxiang
作者机构:
关键词: Hydrophilic interaction liquid chromatography tandem mass spectrometry;Dipyrone;Metabolites;Residues;Goat;Tissues
期刊名称:FOOD CHEMISTRY ( 影响因子:7.514; 五年影响因子:7.516 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: A reliable LC-MS/MS method with high sensitivity was developed and validated for the determination of dipyrone (DIP) metabolites in goat muscle, fat, liver, and kidney samples. Analytes were extracted using acetonitrile mixed with ammonia solution. After dehydration and evaporation to dryness, extracts were purified using an Oasis MAX cartridge. Chromatographic separation was performed on a hydrophilic interaction liquid chromatography column. The analytes were then detected using triple-quadrupole mass spectrometry in positive electrospray ionization and multiple reaction monitoring mode. Calibration plots were constructed using matrix-matched standards and showed good linearity. Limits of quantification for 4-methylaminoantipyrine (MM), 4-formylaminoantipyrine (FAA), and 4-acetylaminoantipyrone (AAA) ranged from 0.41 mu kg(-1) to 6 mu g kg(-1), while those for 4-aminoantipyrone (AA) ranged from 10 mu g kg(-1) to 125 mu g kg(-1) in all tissues. The developed method was successfully applied in the determination of DIP metabolite residues in actual goat tissues. (C) 2015 Elsevier Ltd. All rights reserved.
分类号: TS2`TS201.2
- 相关文献
作者其他论文 更多>>
-
Genome-wide association studies dissect low-phosphorus stress response genes underling field and seedling traits in maize
作者:Luo, Bowen;Gao, Shibin;Luo, Bowen;Zhang, Guidi;Yu, Ting;Zhang, Chong;Yang, Guohui;Luo, Xianfu;Zhang, Shuhao;Guo, Jianyong;Zhang, Haiying;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Luo, Bowen;Zhang, Guidi;Yu, Ting;Zhang, Chong;Yang, Guohui;Luo, Xianfu;Zhang, Shuhao;Guo, Jianyong;Zhang, Haiying;Zhang, Xiao;Liu, Dan;Wu, Ling;Gao, Duojiang;Gao, Shiqiang;Gao, Shibin;Zheng, Hao;Tang, Zirui;Li, Qile;Lan, Yuzhou;Ma, Peng;Ma, Peng;Nie, Zhi;Su, Shunzong;Guo, Jia
关键词:
-
Multiple strategies, including 6mA methylation, affecting plant alternative splicing in allopolyploid peanut
作者:Wang, Lihui;Chen, Kun;Fu, Huiwen;Chen, Hua;Zhang, Chong;Cai, Tiecheng;Yang, Qiang;Zhuang, Weijian;Zhuang, Yuhui;Chen, Xiangyu;Chitkineni, Annapurna;Varshney, Rajeev K.;Wang, Xiyin
关键词:peanut; alternative splicing; chromatin structures; Iso-Seq; 6mA
-
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca2+signaling pathway
作者:Zhu, Mingkun;Yan, Ming;Musa, Maierhaba;Li, Yurong;Zhang, Yeshun;Zhu, Mingkun;Yan, Ming;Musa, Maierhaba;Li, Yurong;Zhang, Yeshun;Zou, Xiaoting
关键词:Cadmium; Granulosa cell; Apoptosis; MCU; Ca 2+signaling pathway; Laying hens
-
Novel material-oriented valorization of biogas can achieve more carbon reduction than traditional utilization by bioelectricity or biomethane
作者:Guo, Jing;He, Pinjing;Li, Chao;Zhang, Hua;Lue, Fan;Guo, Jing;He, Pinjing;Li, Chao;Zhang, Hua;Wu, Hao;Zhou, Jun;Liao, Jingwen;Xi, Yonglan
关键词:Biogas upgrading; Biomethane; Climate change impact; Carbon sequestration; Biogas management
-
Engineered Peptides Harboring Cation Motifs Against Multidrug-Resistant Bacteria
作者:Shang, Lu;Chen, Chan;Sun, Rui;Guo, Juan;Liu, Jing;Wang, Mi;Zhang, Lifang;Fei, Chenzhong;Xue, Feiqun;Liu, Yingchun;Gu, Feng;Shang, Lu;Chen, Chan;Sun, Rui;Guo, Juan;Liu, Jing;Wang, Mi;Zhang, Lifang;Fei, Chenzhong;Xue, Feiqun;Liu, Yingchun;Gu, Feng
关键词:antibiotic resistance; multidrug-resistant pathogens; antimicrobial peptide; biosafety; biofilm
-
Identification and Validation of Magnolol Biosynthesis Genes in Magnolia officinalis
作者:Yang, Yue;Li, Zihe;Zong, Hang;Li, Zhenzhu;Wang, Wen;Liu, Shimeng;Du, Qiuhui;Wu, Hao;Wang, Xiao;Huang, Lihui;Lai, Changlong;Chen, Xianqing;Zhang, Meide
关键词:Magnolia officinalis; transcripts; in vitro; magnolol synthesis; enzyme activity
-
Characterization of ZmCesAs for Secondary Cell Wall Biosynthesis in Maize
作者:Zhang, Yuting;Wu, Hao;Li, Xin;Ge, Yufang;Lu, Xiaoduo;Li, Haiyan;Lu, Xiaoduo;Lu, Xiaoduo
关键词:Maize; Cellulose; CesA; Secondary cell wall; Molecular network; Marker