Cinnamaldehyde inhibits fungal growth and aflatoxin B-1 biosynthesis by modulating the oxidative stress response of Aspergillus flavus

文献类型： 外文期刊

第一作者： Sun, Qi

作者： Sun, Qi;Shang, Bo;Liu, Yang;Wang, Ling;Lu, Zhisong

作者机构：

关键词： Aspergillus flavus;Aflatoxin B-1;Cinnamaldehyde;Inhibitory activities;Oxidative stress;Redox status

期刊名称：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY （ 影响因子：4.813； 五年影响因子：4.697 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Cinnamaldehyde (CIN) is a promising natural preservative and generally recognized as safe for commodities as well as consumers. In this work, the antifungal effects of CIN on Aspergillus flavus were evaluated both in solid and in liquid culture conditions. Our results indicated that CIN effectively inhibited radial growth, spore production, mycelium formation, and aflatoxin B-1 biosynthesis by A. flavus in a dose-dependent manner. At the concentration of 104 mg L-1, CIN exposure was able to completely inhibit fungal growth as well as aflatoxin B-1 production. Furthermore, the inhibitory activities of CIN were closely connected with the treatment period and the tested fungal species. Compared with the control strains, CIN dose dependently changed the morphology and ultrastructure of mycelium in different degree. Especially, the reduction of hydrogen peroxide was considered to follow the destruction of mitochondrial. Meanwhile, CIN significantly cut the levels of lipid peroxidation and reduced glutathione. The activity of total superoxide dismutase was significantly inhibited after CIN treatment at the end of incubation, whereas the activities of catalase and glutathione peroxidase were opposite. These results indicated that the inhibitory effect of CIN could attribute to oxidative stress alleviation possibly induced by modifications of cellular structure as well as redox status.

分类号： Q939.9`Q81

  • 相关文献

[1]Ethylene inhibited aflatoxin biosynthesis is due to oxidative stress alleviation and related to glutathione redox state changes in Aspergillus flavus. Liao, B. -S.. 2009

[2]Effects of dietary pyrroloquinoline quinone disodium on growth, carcass characteristics, redox status, and mitochondria metabolism in broilers. Wang, J.,Zhang, H. J.,Samuel, K. G.,Long, C.,Wu, S. G.,Yue, H. Y.,Qi, G. H.,Sun, L. L..

[3]Effect of cinnamaldehyde on melanosis and spoilage of Pacific white shrimp (Litopenaeus vannamei) during storage. Mu, Honglei,Chen, Hangjun,Fang, Xiangjun,Mao, Jinlin,Gao, Haiyan. 2012

[4]Cinnamaldehyde Induces PCD-Like Death of Microcystis aeruginosa via Reactive Oxygen Species. Hu, Liang Bin,Zhou, Wei,Yang, Jing Dong,Chen, Jian,Yin, Yu Fen,Shi, Zhi Qi,Hu, Liang Bin,Hu, Liang Bin,Zhou, Wei,Yang, Jing Dong,Shi, Zhi Qi. 2011

[5]Growth inhibition and morphological alterations of Fusarium verticillioides by cinnamon oil and cinnamaldehyde. Xing, Fuguo,Hua, Huijuan,Selvaraj, Jonathan Nimal,Zhao, Yueju,Zhou, Lu,Liu, Xiao,Liu, Yang.

[6]In vitro anti-aflatoxigenic effect and mode of action of cinnamaldehyde against aflatoxin B-1. Sun, Qi,Liu, Yang,Wang, Ling,Lu, Zhisong.

[7]Effects of wheat dried distillers' grains with solubles and cinnamaldehyde on in vitro fermentation and protein degradation using the Rusitec technique. Li, Yangling,He, Maolong,Li, Chun,Forster, Robert,Beauchemin, Karen Anne,Yang, Wenzhu,Li, Yangling,Li, Chun.

[8]Cinnamaldehyde promotes root branching by regulating endogenous hydrogen sulfide. Xue, Yan-Feng,Zhang, Meng,Qi, Zhong-Qiang,Li, You-Qin,Shi, Zhiqi,Chen, Jian,Xue, Yan-Feng,Zhang, Meng,Qi, Zhong-Qiang,Li, You-Qin,Shi, Zhiqi,Chen, Jian.

[9]Cinnamaldehyde Ameliorates Cadmium-Inhibited Root Elongation in Tobacco Seedlings via Decreasing Endogenous Hydrogen Sulfide Production. Ye, Xie-Feng,Ling, Tianxiao,Yu, Xiao-Na,Xue, Yanfeng,Wang, Yong,Cheng, Changxin,Feng, Guosheng,Hu, Liangbin,Shi, Zhiqi,Chen, Jian,Shi, Zhiqi,Chen, Jian.

[10]Isolation and characterization of Aspergillus flavus strains in China. Mamo, Firew Tafesse,Wang, Yan,Liu, Yang,Mamo, Firew Tafesse,Wang, Yan,Liu, Yang,Shang, Bo,Selvaraj, Jonathan Nimal. 2018

[11]Optimization of Aflatoxin Production of Aspergillus Flavus on peanuts. Zhang Chushu,Sun Jie,Yu Lina,Yang Qingli,Feng Jianxiong. 2014

[12]Study on the key environmental factors Aspergillus flavus growth and aflatoxin production. Zhang Chushu,Sun Jie,Yu Lina,Bi Jie,Yang Qingli,Zhao Qin,Feng Jianxiong,Fu Xiaoji,Gao Yanan. 2014

[13]Gene Expression Profiling and Identification of Resistance Genes to Aspergillus flavus Infection in Peanut through EST and Microarray Strategies. Bhatnagar, Deepak,Yu, Jiujiang,Guo, Baozhu,Fedorova, Natalie D.,Wan, Chun-Hua,Wang, Wei,Nierman, William C.,Chen, Xiaoping,Chen, Xiaoping,Nierman, William C.. 2011

[14]A strain of Aspergillus flavus from China shows potential as a biocontrol agent for aflatoxin contamination. Zhou, Lu,Wei, Dan-Dan,Selvaraj, Jonathan Nimal,Shang, Bo,Zhang, Chu-Shu,Xing, Fu-Guo,Zhao, Yue-Ju,Wang, Yan,Liu, Yang.

[15]Aflatoxin B-1 inhibition in Aspergillus flavus by Aspergillus niger through down-regulating expression of major biosynthetic genes and AFB(1) degradation by atoxigenic A. flavus. Xing, Fuguo,Wang, Limin,Liu, Xiao,Selvaraj, Jonathan Nimal,Wang, Yan,Zhao, Yueju,Liu, Yang.

[16]Development and evaluation of ITS- and aflP-based LAMP assays for rapid detection of Aspergillus flavus in food samples. Liu, Peiqing,Li, Benjin,Yin, Rongmei,Weng, Qiyong,Chen, Qinghe.

[17]Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. Yan, Shijuan,Chen, Zhuang,Yan, Shijuan,Liang, Yating,Zhang, Jindan,Liu, Chun-Ming.

[18]Development of an Enzyme-Linked Immunosorbent Assay Method Specific for the Detection of G-Group Aflatoxins. Li, Peiwu,Zhou, Qian,Wang, Ting,Zhou, Haiyan,Zhang, Wen,Ding, Xiaoxia,Zhang, Zhaowei,Zhang, Qi,Li, Peiwu,Zhou, Haiyan,Zhang, Wen,Ding, Xiaoxia,Zhang, Zhaowei,Zhang, Qi,Li, Peiwu,Zhou, Haiyan,Zhang, Wen,Ding, Xiaoxia,Zhang, Zhaowei,Zhang, Qi,Li, Peiwu,Zhou, Haiyan,Zhang, Wen,Ding, Xiaoxia,Zhang, Zhaowei,Zhang, Qi,Zhou, Qian,Chang, Perng-Kuang. 2016

[19]Effect of water activity and temperature on the growth of Aspergillus flavus, the expression of aflatoxin biosynthetic genes and aflatoxin production in shelled peanuts. Liu, Xiao,Guan, Xuanli,Xing, Fuguo,Lv, Cong,Dai, Xiaofeng,Liu, Yang.

[20]The effectiveness of ISSR profiling for studying genetic diversity of Aspergillus flavus from peanut-cropped soils in China. Zhang, Chu-Shu,Xing, Fu-Guo,Selvaraj, Jonathan Nimal,Zhou, Lu,Zhao, Yue-Ju,Liu, Yang,Zhang, Chu-Shu,Yang, Qing-Li.

作者其他论文 更多>>

微信小程序