The effects of Mycoplasma hyopneumoniae on porcine circovirus type 2 replication in vitro PK-15 cells

文献类型: 外文期刊

第一作者: Wang, Haiyan

作者: Wang, Haiyan;Feng, Zhixin;Wu, Yuzi;Wei, Yanna;Gan, Yuan;Hua, Lizhong;Li, Bin;Wang, Xiaomin;Liu, Maojun;Xiong, Qiyan;Shao, Guoqing;Wang, Haiyan;Feng, Zhixin;Shao, Guoqing

作者机构:

关键词: Porcine circovirus type 2;Mycoplasma hyopneumoniae;Co-infection;Replication

期刊名称:RESEARCH IN VETERINARY SCIENCE ( 影响因子:2.534; 五年影响因子:2.382 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Porcine circovirus type 2 (PCV2) is the causative agent of postweaning multisystemic wasting syndrome (PMWS). Mycoplasma hyopneumoniae (Mhp) is a very well-known co-factor that potentially enhances PCV2 replication and thus the development of PMWS. However, co-infection with Mhp and PCV2 in vivo under different conditions can produce divergent clinical signs and lesions. In this study, PCV2 replication could be enhanced by subsequent co-inoculation with Mhp (PCV2 + Mhp) in a time and dose dependent method, but not by prior (Mhp + PCV2) or simultaneous (Mhp/PCV2) co-inoculation. Furthermore, different magnitudes of PCV2-infected cells, varying from 150% +/- 14% to 351% +/- 28%, were detected when co-infected with different Mhp strains. The relative percentage of PCV2-infected cells greatly decreased from 351%+/- 28 to 141%+/- 8 when the Mhp strain was treated with UV light for 12 h. These results offer the evidences to better understand the complex clinical syndromes in Mhp/PCV2 co-infection cases, and the occurrence of PMWS. (C) 2016 Published by Elsevier Ltd.

分类号: S85

  • 相关文献

[1]Transcription analysis on response of porcine alveolar macrophages to co-infection of the highly pathogenic porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. Li, Bin,Du, Luping,Xu, Xiangwei,Sun, Bing,Yu, Zhengyu,Feng, Zhixin,Liu, Maojun,Wei, Yanna,Wang, Haiyan,Shao, Guoqing,He, Kongwang,Li, Bin,Yu, Zhengyu,Feng, Zhixin,Liu, Maojun,Wei, Yanna,Wang, Haiyan,Shao, Guoqing,He, Kongwang.

[2]Co-Infection with Marek's Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek's Disease Vaccine Efficacy. Sun, Guo-Rong,Zhang, Yan-Ping,Zhou, Lin-Yi,Lv, Hong-Chao,Zhang, Feng,Li, Kai,Gao, Yu-Long,Qi, Xiao-Le,Cui, Hong-Yu,Wang, Yong-Qiang,Gao, Li,Pan, Qing,Wang, Xiao-Mei,Liu, Chang-Jun. 2017

[3]Porcine bocaviruses: genetic analysis and prevalence in Chinese swine population. Zhang, H. B.,Huang, L.,Lin, T.,Sun, C. Q.,Deng, Y.,Wei, Z. Z.,Long, J. X.,Yuan, S. S.,Zhang, H. B.,Liu, Y. J.,Lin, T.,Cheung, A. K.. 2011

[4]Establishment of a Multiplex PCR and an Investigation of Co-Infection Rate of WSSV and IHHNV in Penaeid vannamei in Northern of Jiangsu. Chen, Yi-Bing,Gao, Song,Zhou, Jun-Fang,Wan, Xi-He. 2012

[5]Concurrent highly pathogenic porcine reproductive and respiratory syndrome virus infection accelerates Haemophilus parasuis infection in conventional pigs. Wang, Jinbao,Yu, Jiang,Wang, Jinbao. 2012

[6]Co-infection of H9N2 subtype avian influenza virus and infectious bronchitis virus decreases SP-A expression level in chickens. Huang, Qi,Wang, Kai,Pan, Ling,Qi, Kezong,Liu, Hongmei,Huang, Qi,Wang, Kai,Chen, Hongjun.

[7]The Cap Snatching of Segmented Negative Sense RNA Viruses as a Tool to Map the Transcription Start Sites of Heterologous Co-infecting Viruses. Lin, Wenzhong,Qiu, Ping,Jin, Jing,Liu, Shunmin,Ul Islam, Saif,Zhang, Jie,Du, Zhenguo,Wu, Zujian,Yang, Jinguang,Kormelink, Richard,Du, Zhenguo,Wu, Zujian. 2017

[8]The occurrence of porcine circovirus 3 without clinical infection signs in Shandong Province. Zheng, S.,Wu, X.,Zhang, L.,Xin, C.,Shi, J.,Peng, Z.,Xu, S.,Yu, J.,Sun, W.,Xu, S.,Li, J.,Wang, J.,Zheng, S.,Liu, Y.,Fu, F..

[9]Development and validation of an attenuated Mycoplasma hyopneumoniae aerosol vaccine. Feng, Zhi-Xin,Wei, Yan-Na,Li, Gui-Lan,Lu, Xiao-Ming,Wang, Zhan-Wei,Kong, Meng,Gan, Yuan,Bai, Fang-Fang,Liu, Mao-Jun,Xiong, Qi-Yan,Wu, Xu-Su,Shao, Guo-Qing,Wan, Xiu-Feng,Pharr, G. Todd. 2013

[10]A rapid and sensitive loop-mediated isothermal amplification procedure (LAMP) for Mycoplasma hyopneumoniae detection based on the p36 gene. Liu, M. J.,Du, G. M.,Bai, F. F.,Wu, Y. Z.,Xiong, Q. Y.,Feng, Z. X.,Li, B.,Shao, G. Q.,Du, G. M.,Liu, M. J.,Shao, G. Q.. 2015

[11]Immune Responses to the Attenuated Mycoplasma hyopneumoniae 168 Strain Vaccine by Intrapulmonic Immunization in Piglets. Feng Zhi-xin,Shao Guo-qing,Liu Mao-jun,Wu Xu-su,Zhou Yong-qi,Gan Yuan. 2010

[12]Cholesterol exacerbates Mycoplasma hyopneumoniae-induced apoptosis via stimulating proliferation and adhesion to porcine alveolar macrophages. Liu, Maojun,Hu, Yun,Liu, Jie,Jia, Yimin,Zhao, Ruqian,Liu, Maojun,Liu, Beibei,Shao, Guoqing,Jia, Yimin,Zhao, Ruqian,Du, Gaimei,Minion, F. Chris,Shao, Guoqing. 2017

[13]CYP1A1 mediates the suppression of major inflammatory cytokines in pulmonary alveolar macrophage (PAM) cell lines caused by Mycoplasma hyponeumoniae. Fang, Xiaomin,Zhao, Weimin,Xu, Jie,Tu, Feng,Wang, Xuemin,Li, Bixia,Fu, Yanfeng,Ren, Shouwen.

[14]Apoptosis induced by lipid-associated membrane proteins from Mycoplasma hyopneumoniae in a porcine lung epithelial cell line with the involvement of caspase 3 and the MAPK pathway. Ni, B.,Bai, F. F.,Wei, Y.,Liu, M. J.,Feng, Z. X.,Xiong, Q. Y.,Hua, L. Z.,Shao, G. Q.. 2015

[15]Loop-mediated isothermal amplification for rapid and convenient detection of Mycoplasma hyopneumoniae. Li, Jiahe,Jiang, Fei,Yang, Sheng,Guo, Panpan,Wu, Wenxue,Minion, F. Chris,Petersen, Andrew C.,Li, Jinxiang.

[16]Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NF kappa B and MAPK pathways in RAW264.7 cells. Hwang, Mi-Hyun,Damte, Dereje,Lee, Joong-Su,Gebru, Elias,Chang, Zhi-Qiang,Rhee, Man-Hee,Park, Seung-Chun,Cheng, Henrique,Jung, Byeong-Yeal,Chang, Zhi-Qiang. 2011

[17]Development of a blocking ELISA for detection of Mycoplasma hyopneumoniae infection based on a monoclonal antibody against protein P65. Liu, Maojun,Zhang, Yue,Wu, Yuzi,Wang, Haiyan,Li, Bin,Bai, Yun,Feng, Zhixin,Xiong, Qiyan,Bai, Fangfang,Shao, Guoqing,Liu, Maojun,Du, Gaimei,Browning, Glenn F.,Shao, Guoqing.

[18]Effect of different adjuvant formulations on the immunogenicity and protective effect of a live Mycoplasma hyopneumoniae vaccine after intramuscular inoculation. Wang, Chunlai,Xie, Fang,Xiong, Qiyan,Wei, Yanna,Xie, Haidong,Feng, Zhixin,Gan, Yuan,Liu, Maojun,Bai, Fangfang,Shao, Guoqing.

[19]Comparative genomic analyses of Mycoplasma hyopneumoniae pathogenic 168 strain and its high-passaged attenuated strain. Liu, Wei,Xiao, Shaobo,Li, Mao,Guo, Shaohua,Li, Sha,Luo, Rui,Chen, Huanchun,Fang, Liurong,Feng, Zhixin,Li, Bin,Shao, Guoqing,Zhou, Zhemin. 2013

[20]Comparative analysis of mucosal immunity to Mycoplasma hyopneumoniae in Jiangquhai porcine lean strain and DLY piglets. Hua, L. Z.,Wu, Y. Z.,Bai, F. F.,William, K. K.,Feng, Z. X.,Liu, M. J.,Yao, J. T.,Zhang, X.,Shao, G. Q.. 2014

作者其他论文 更多>>