Enhancement of Nutraceutical Bioavailability using Excipient Nanoemulsions: Role of Lipid Digestion Products on Bioaccessibility of Carotenoids and Phenolics from Mangoes

文献类型: 外文期刊

第一作者: Liu, Xuan

作者: Liu, Xuan;Bi, Jinfeng;Liu, Xuan;Xiao, Hang;McClements, David Julian;Xiao, Hang;McClements, David Julian;McClements, David Julian

作者机构:

关键词: carotenoids;bioaccessibility;excipient emulsions;nutraceuticals;phenolics

期刊名称:JOURNAL OF FOOD SCIENCE ( 影响因子:3.167; 五年影响因子:3.376 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: The ability of excipient nanoemulsions to increase the bioaccessibility of different kinds of nutraceuticals (phenolics and carotenoids) in mangoes was studied. Oil-in-water excipient nanoemulsions containing small digestible lipid nanoparticles (d < 200 nm) were prepared using different oil phases: medium chain triglycerides (MCT) and long-chain triglycerides (LCT). These nanoemulsions were then mixed with pureed mango and passed through a simulated gastrointestinal tract (GIT): mouth, stomach, and small intestine. Carotenoid bioaccessibility decreased in the following order: LCT nanoemulsions > MCT nanoemulsions > buffer solution, which was attributed to differences in the solubilization capacity of the mixed micelles generated in the intestinal fluids. The digestion products of LCT formed mixed micelles with hydrophobic domains large enough to accommodate the carotenoids, whereas those of MCT did not. Excipient emulsions had much less effect on phenolic bioaccessibility, which may be because phenolics are smaller more polar molecules and are therefore more easily solubilized in aqueous intestinal fluids. These results highlight the potential of excipient nanoemulsions in boosting the bioavailability of lipophilic bioactive agents in fruits and vegetables.

分类号: TS2

  • 相关文献

[1]Increasing Carotenoid Bioaccessibility from Yellow Peppers Using Excipient Emulsions: Impact of Lipid Type and Thermal Processing. Liu, Xuan,Bi, Jinfeng,Liu, Xuan,Xiao, Hang,McClements, David Julian,Xiao, Hang,McClements, David Julian,McClements, David Julian.

[2]Particle size of insoluble dietary fiber from rice bran affects its phenolic profile, bioaccessibility and functional properties. Zhao, Guanghe,Zhang, Ruifen,Zhao, Guanghe,Zhang, Ruifen,Dong, Lihong,Huang, Fei,Tang, Xiaojun,Wei, Zhencheng,Zhang, Mingwei. 2018

[3]Different thermal drying methods affect the phenolic profiles, their bioaccessibility and antioxidant activity in Rhodomyrtus tomentosa (Ait.) Hassk berries. Zhao, Guanghe,Zhang, Ruifen,Liu, Lei,Deng, Yuanyuan,Wei, Zhencheng,Zhang, Yan,Ma, Yongxuan,Zhang, Mingwei,Zhao, Guanghe,Zhang, Ruifen,Liu, Lei,Deng, Yuanyuan,Wei, Zhencheng,Zhang, Yan,Ma, Yongxuan,Zhang, Mingwei,Zhao, Guanghe,Zhang, Ruifen.

[4]Characterization of the Appearance, Health-Promoting Compounds, and Antioxidant Capacity of the Florets of the Loose-Curd Cauliflower. Gu, Honghui,Wang, Jiansheng,Zhao, Zhenqing,Sheng, Xiaoguang,Yu, Huifang,Huang, Wenbin. 2015

[5]Tangeretin-loaded protein nanoparticles fabricated from zein/beta-lactoglobulin: Preparation, characterization, and functional performance. Chen, Jingjing,Zheng, Jinkai,McClements, David Julian,Xiao, Hang,Zheng, Jinkai. 2014

[6]A Comparison of the Chemical Composition, In Vitro Bioaccessibility and Antioxidant Activity of Phenolic Compounds from Rice Bran and Its Dietary Fibres. Zhao, Guanghe,Zhang, Ruifen,Dong, Lihong,Huang, Fei,Liu, Lei,Deng, Yuanyuan,Ma, Yongxuan,Zhang, Yan,Wei, Zhencheng,Xiao, Juan,Zhang, Mingwei,Zhao, Guanghe,Zhang, Ruifen. 2018

[7]Bioaccessibility of Microamount Metal Elements in Oyster and Cam Samples Using in vitro Digestion. Wang Zeng-Huan,Wang Xu-Nuo,Lin Qin,Chen Cheng-Tong,Chen Ying-Na. 2016

[8]Impact of Lipid Phase on the Bioavailability of Vitamin E in Emulsion-Based Delivery Systems: Relative Importance of Bioaccessibility, Absorption, and Transformation. Yang, Ying,Yang, Ying,Xiao, Hang,McClements, David Julian.

[9]Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment. Kang, Yuan,Li, Laisheng,Zhang, Qiuyun,Zeng, Lixuan,Luo, Jiwen,Kang, Yuan,Man, Yubon,Wong, Ming Hung,Kang, Yuan,Man, Yubon,Wong, Ming Hung,Yin, Yi.

[10]Effect of modifier on the composition and antioxidant activity of carotenoid extracts from pumpkin (Cucurbita maxima) by supercritical CO2. Shi, Xianquan,Wang, Wenliang,Cheng, Anwei,Gong, Zhiqing,Chen, Xiangyan,Wu, Hao,Shi, John,Xue, Sophia Jun,Wu, Hao,Wang, Chengrong,Wang, Dongfeng. 2013

[11]Comparison of Four Types of Raman Spectroscopy for Noninvasive Determination of Carotenoids in Agricultural Products. Wang, Qingyan,Huang, Wenqian,Chen, Liping,Wang, Qingyan,Huang, Wenqian,Chen, Liping,Wang, Qingyan,Huang, Wenqian,Chen, Liping,Wang, Qingyan,Huang, Wenqian,Chen, Liping,Liu, Chen,Chen, Liping,Fan, Shuxiang,Zhang, Baohua. 2016

[12]Degradation kinetics of carotenoids and visual colour in pumpkin (Cucurbita maxima L.) slices during microwave-vacuum drying. Song, Jiangfeng,Wang, Xiaoping,Li, Dajing,Liu, Chunquan,Wang, Xiaoping. 2017

[13]An integration of photosynthetic traits and mechanisms that can increase crop photosynthesis and grain production. Black, CC,Tu, ZP,Counce, PA,Yao, PF,Angelov, MN. 1995

[14]Biochemical and transcriptomic analyses reveal different metabolite biosynthesis profiles among three color and developmental stages in 'Anji Baicha' (Camellia sinensis). Li, Chun-Fang,Xu, Yan-Xia,Ma, Jian-Qiang,Jin, Ji-Qiang,Huang, Dan-Juan,Yao, Ming-Zhe,Ma, Chun-Lei,Chen, Liang,Li, Chun-Fang. 2016

[15]Polyphasic and Biosynthetic Genes Investigation of Five Carotenoid-producing Bacteria Strains Isolated from East China Sea. Yang Qiao,Zhang Xiaoling. 2010

[16]Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice. Yu, Huifeng,Wark, Logan,Ji, Hua,Jaing, Yu,Han, Jing,Ortiz, Edlin,Zhang, Yunong,Medeiros, Denis M.,Lin, Dingbo,Ji, Hua,He, Hui,Willard, Lloyd,Medeiros, Denis M.. 2013

[17]In silico identification and analysis of phytoene synthase genes in plants. Han, Y.,Chen, J.,Zheng, Q. S.,Liu, R.,Wei, Y. P.,Wei, Y. P.,Liu, R.,Wan, H. J.. 2015

[18]Isolation and Polyphasic Investigation of the Carotenoids-producing Marine Bacterium from Trachurus murphyi Chile Fishery. Zhang, Xiaoling,Yang, Qiao,Zhang, Heng,Huang, Hongliang. 2013

[19]Effects of Carotenoids on The Radioresistance of The Extremely Radioresistant Bacterium Deinococcus radiodurans. Yang Qiao,Jiao Bing-Hua,Yang Qiao,Zhang Lei,Dai Jun,Zhang Jun-Xiang,Zhang Xiao-Ling. 2009

[20]The impact of elevated ozone on the ornamental features of two flowering plants (Tagetes erecta linn. Petunia hybrida Vilm.). Yang, Ning,Wang, Xiaoke,Chen, Yuanyuan,Yang, Ning,Zheng, Feixiang.

作者其他论文 更多>>