Use of liquid chromatography-quadrupole time-of-flight mass spectrometry for enantioselective separation and determination of pyrisoxazole in vegetables, strawberry and soil

文献类型： 外文期刊

第一作者： Qi, Peipei

作者： Qi, Peipei;Yuan, Yuwei;Wang, Zhiwei;Wang, Xiangyun;Xu, Hao;Zhang, Hu;Wang, Qiang;Wang, Xinquan;Qi, Peipei;Yuan, Yuwei;Wang, Zhiwei;Wang, Xiangyun;Xu, Hao;Zhang, Hu;Wang, Qiang;Wang, Xinquan;Qi, Peipei;Yuan, Yuwei;Wang, Zhiwei;Wang, Xiangyun;Xu, Hao;Zhang, Hu;Wang, Qiang;Wang, Xinquan;Qi, Peipei;Yuan, Yuwei;Wang, Zhiwei;Wang, Xiangyun;Xu, Hao;Zhang, Hu;Wang, Qiang;Wang, Xinquan

作者机构：

关键词： Pyrisoxazole;LC-Q-TOF/MS;Chiral enantiomer;Degradation kinetic

期刊名称：JOURNAL OF CHROMATOGRAPHY A （ 影响因子：4.759； 五年影响因子：4.302 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The present work firstly described the enantio-separation and determination of pyrisoxazole enantiomers in vegetables, strawberry and soil samples by chiral liquid chromatography coupled to quadrupole time of-flight mass spectrometry (LC-Q-TOF/MS). Pyrisoxazole has two chiral carbon atoms and consists of four stereoisomers. Taking the specific optical rotation measurement and MS analysis data into consideration, the four enantiomers were discriminated as (-)-A, (+)-A, (+)-B and (-)-B corresponding to their elution order under the optimum chromatographic condition. Influences of the mobile phase and column temperature on the enantio-separation selectivity of pyrisoxazole were explored. The perfect baseline separation of pyrisoxazole enantiomers can be achieved within 10 min using methanol-water (70:30, v/v) as mobile phase on chiral Lux Cellulose-3 column. The thermodynamic analysis demonstrated that the enantioseparation of (-)-A and (+)-A, (+)-A and (+)-B were enthalpy driven separation, while the enantioseparation of (+)-B and (-)-B was entropy driven separation. Under the optimum method, method validation including matrix effect, linearity, sensitivity and precision were performed. At the spiked concentration of 10, 50 and 100 1.14 kg(-1), the recoveries of the pyrisoxazole enantiomers in cucumber, tomato, pakchoi, pepper and strawberry samples were 64.2-100% (RSD <= 14%); While they were relatively higher in soil samples and all around 120% (RSD <= 10%). The limits of detection are in the range from 0.2 to 1.0 mu g kg(-1) for cucumber, tomato, pakchoi, pepper, strawberry and soil samples. The developed method was then utilized for monitoring the degradation kinetics of pyrisoxazole enantiomers in strawberry under field trials, which provided the environmental behavior data of chiral pyrisoxazole enantiomers and consequently for further health risk assessment of the chiral pesticides. (C) 2016 Elsevier B.V. All rights reserved.

分类号： O65

  • 相关文献

[1]Degradation kinetics of cyanidin 3-O-glucoside and cyanidin 3-O-rutinoside during hot, air and vacuum drying in mulberry (Morus alba L.) fruit: A comparative study based on solid food system. Zhou, Mo,Chen, Qinqin,Bi, Jinfeng,Wang, Yixiu,Wu, Xinye.

[2]Stereoselective analysis of novel chiral fungicide pyrisoxazole in cucumber, tomato and soil under different application methods with supercritical fluid chromatography/tandem mass spectrometry. Dong, Fengshou,Xu, Jun,Liu, Xingang,Chen, Zenglong,Zheng, Yongquan.

[3]Stereoselective Analysis and Degradation of Pyrisoxazole in Cabbage, Pakchoi, and Pepper by Liquid Chromatography Tandem Mass Spectrometry. Yang, Xuewei,Sun, Yuhan,Wang, Lidong,Zhao, Changshan,Qi, Peipei,Wang, Xiangyun,Wang, Zhiwei,Xu, Xiahong,Xu, Hao,Wang, Qiang,Wang, Xinquan,Qi, Peipei,Wang, Xiangyun,Wang, Zhiwei,Xu, Xiahong,Xu, Hao,Wang, Qiang,Wang, Xinquan,Qi, Peipei,Wang, Xiangyun,Wang, Zhiwei,Xu, Xiahong,Xu, Hao,Wang, Qiang,Wang, Xinquan.

作者其他论文 更多>>

微信小程序