Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala)

文献类型： 外文期刊

第一作者： Habte-Tsion, Habte-Michael

作者： Habte-Tsion, Habte-Michael;Ren, Mingchun;Liu, Bo;Ge, Xianping;Xie, Jun;Ren, Mingchun;Liu, Bo;Ge, Xianping;Xie, Jun;Chen, Ruli;Habte-Tsion, Habte-Michael

作者机构：

关键词： Blunt snout bream (Megalobrama amblycephala);Threonine;Immune response;Antioxidant capacity;Antioxidant-immune-cytokine-related signaling molecule

期刊名称：FISH & SHELLFISH IMMUNOLOGY （ 影响因子：4.581； 五年影响因子：4.851 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： A 9-week feeding trial was conducted to investigate the effects of graded dietary threonine (Thr) levels (0.58-2.58%) on the hematological parameters, immune response, antioxidant status and hepatopancreatic gene expression of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream. For this purpose, 3 tanks were randomly arranged and assigned to each experimental diet. Fish were fed with their respective diet to apparent satiation 4 times daily. The results indicated that white blood cell, red blood cell and haemoglobin significantly responded to graded dietary Thr levels, while hematocrit didn't. Complement components (C3 and C4), total iron-binding capacity (TIBC), immunoglobulin M (IgM), superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) increased with increasing dietary Thr levels up to 1.58-2.08% and thereafter tended to decrease. Dietary Thr regulated the gene expressions of Cu/Zn-SOD, Mn-SOD and CAT, GPx1, glutathione S-transferase mu (GST), nuclear factor erythroid 2-related factor 2 (Nrf2), heat shock protein-70 (Hsp70), tumor necrosis factor-alpha (TNF-alpha), apolipoprotein A-I (ApoA1), glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and fructose-bisphosphate aldolase B (ALDOB); while the gene expression of peroxiredoxin II (PrxII) was not significantly modified by graded Thr levels. These genes are involved in different functions including antioxidant, immune, and defense responses, energy metabolism and protein synthesis. Therefore, this study could provide a new molecular tool for studies in fish immunonutrition and shed light on the regulatory mechanisms that dietary Thr improved the antioxidant and immune capacities of fish. (C) 2015 Elsevier Ltd. All rights reserved.

分类号： S9

  • 相关文献

[1]Dietary leucine modulates growth performance, Nrf2 antioxidant signaling pathway and immune response of juvenile blunt snout bream (Megalobrama amblycephala). Liang, Hualiang,Mokrani, Ahmed,Ji, Ke,Ge, Xianping,Ren, Mingchun,Xie, Jun,Liu, Bo,Ge, Xianping,Ren, Mingchun,Xie, Jun,Liu, Bo,Xi, Bingwen,Zhou, Qunlan. 2018

[2]Dietary leucine level affects growth performance, whole body composition, plasma parameters and relative expression of TOR and TNF-alpha in juvenile blunt snout bream, Megalobrama amblycephala. Ren, Mingchun,Liu, Bo,Miao, Linghong,Ge, Xianping,Xie, Jun,Zhou, Qunlan,Pan, Liangkun,Ren, Mingchun,Habte-Tsion, Habte-Michael,Liu, Bo,Miao, Linghong,Ge, Xianping,Xie, Jun,Liang, Hualiang,Zhou, Qunlan.

[3]Effects of dietary carbohydrate source on growth performance, diet digestibility and liver glucose enzyme activity in blunt snout bream, Megalobrama amblycephala. Ren, Mingchun,Xie, Jun,Liu, Bo,Zhou, Qunlan,Ge, Xianping,Pan, Liangkun,Chen, Ruli,Ren, Mingchun,Habte-Tsion, Habte-Michael,Xie, Jun,Liu, Bo,Ge, Xianping.

[4]Dietary methionine requirement of juvenile blunt snout bream (Megalobrama amblycephala) at a constant dietary cystine level. Liao, Y. J.,Liu, B.,Cui, H. H.,Xie, J.,Ge, X. P.,Ren, M. C.,Liu, B.,Sun, S. M.,Xie, J.,Zhou, Q. L.,Pan, L. K.,Chen, R. L.,Ge, X. P..

[5]Interactions of dietary protein and threonine on growth performance in Pekin ducklings from 1 to 14 days of age. Jiang, Y.,Xie, M.,Tang, J.,Hou, S. S.,Jiang, Y.,Tang, J.,Qiao, S. Y.,Wen, Z. G.,Zhu, Y. W.. 2018

[6]Threonine affects digestion capacity and hepatopancreatic gene expression of juvenile blunt snout bream (Megalobrama amblycephala). Habte-Tsion, Habte-Michael,Ren, Mingchun,Liu, Bo,Xie, Jun,Ge, Xianping,Zhou, Qunlan,Habte-Tsion, Habte-Michael,Ren, Mingchun,Liu, Bo,Xie, Jun,Ge, Xianping,Chen, Ruli,Zhou, Qunlan,Pan, Liangkun.

[7]Effects of dietary protein on threonine requirements of Pekin ducks from hatch to 21 days of age. Jiang, Y.,Uzma, M.,Tang, T.,Hou, S. S.,Huang, W.,Xie, M.,Jiang, Y.,Tang, T.,Wen, Z. G..

[8]Threonine supplementation reduces dietary protein and improves lipid metabolism in Pekin ducks. Jiang, Y.,Tang, J.,Xie, M.,Hou, S. S.,Jiang, Y.,Tang, J.,Qiao, S. Y.,Wen, Z. G..

[9]Effects of dietary threonine and immune stress on growth performance, carcass trait, serum immune parameters, and intestinal muc2 and NF-kappa b gene expression in Pekin ducks from hatch to 21 days. Bi, Y.,Nan, X. M.,Zheng, S. S.,Xiong, B. H.,Jiang, L. S.. 2018

[10]Threonine influences the absorption capacity and brush-border enzyme gene expression in the intestine of juvenile blunt snout bream (Megalobrama amblycephala). Habte-Tsion, Habte-Michael,Ren, Mingchun,Liu, Bo,Ge, Xianping,Xie, Jun,Zhou, Qunlan,Ren, Mingchun,Liu, Bo,Ge, Xianping,Xie, Jun,Chen, Ruli,Zhou, Qunlan,Pan, Liangkun,Habte-Tsion, Habte-Michael.

[11]Estimation of L-threonine requirements for Longyan laying ducks. Fouad, A. M.,Zhang, H. X.,Chen, W.,Xia, W. G.,Ruan, D.,Wang, S.,Zheng, C. T.,Fouad, A. M..

[12]Influence of Selenium on Hepatic Mitochondrial Antioxidant Capacity in Ducklings Intoxicated with Aflatoxin B-1. Shi, Dayou,Guo, Shining,Su, Rongsheng,Pan, Jiaqiang,Lin, Yuanchao,Tang, Zhaoxin,Liao, Shenquan. 2012

[13]GROWTH PERFORMANCE AND ANTIOXIDANT CAPACITIES IN PIGLETS WITH DIFFERENT WEANING AGE. Li, L. A.,Yang, J. J.,Li, Y.,Jin, T. M.,Li, R. N.,Qin, S. Y.,Xie, J. J.,Du, G. M.. 2016

[14]Effects of dietary methionine on productivity, reproductive performance, antioxidant capacity, ovalbumin and antioxidant-related gene expression in laying duck breeders. Ruan, Dong,Fouad, Ahmed Mohamed,Fan, Qiuli,Xia, Weiguang,Wang, Shuang,Chen, Wei,Lin, Chuxiao,Wang, Ying,Zheng, Chuntian,Ruan, Dong,Yang, Lin,Fouad, Ahmed Mohamed. 2018

[15]Effects of soybean isoflavone on intestinal antioxidant capacity and cytokines in young piglets fed oxidized fish oil. Huang, Lin,Ma, Xian-yong,Jiang, Zong-yong,Hu, You-jun,Zheng, Chun-tian,Yang, Xue-fen,Wang, Li,Gao, Kai-guo. 2016

[16]Quality and consumer acceptance of radio frequency and traditional heat pasteurised kiwi puree during storage. Lyu, Xiaoying,Peng, Xiaoli,Yang, Baowei,Wang, Xin,Baloch, Allah Bux,Xia, Xiaodong,Wang, Shaojin,Yang, Hua,Xiao, Yingping,Yang, Hua,Xiao, Yingping. 2018

[17]Effect of yeast Saccharomyces cerevisiae supplementation on serum antioxidant capacity, mucosal sIgA secretions and gut microbial populations in weaned piglets. Zhu Cui,Wang Li,Wei Shao-yong,Ma Xian-yong,Zheng Chun-tian,Jiang Zong-yong,Zhu Cui,Chen Zhuang,Jiang Zong-yong. 2017

[18]Composition and Antioxidant Capacity of Flour and Hull Extracts from Different Tartary Buckwheat Cultivars. Gong, Xiao,Qi, Ningli,Liu, Yijun,Lin, Lijing,Huang, Maofang. 2014

[19]Effect of hypobaric storage on quality, antioxidant enzyme and antioxidant capability of the Chinese bayberry fruits. Chen, Hangjun,Gao, Haiyan,Long, Jie,Tao, Fei,Fang, Xiangjun,Yang, Hailong,Jiang, Yueming. 2013

[20]Characterization of phenolic profile and antioxidant capacity of different fruit part from lemon (Citrus limon Burm.) cultivars. Xi, Wanpeng,Lu, Juanfang,Qun, Junping,Jiao, Bining,Jiao, Bining.

作者其他论文 更多>>

微信小程序