Isolation and Proteomic Analysis of Rhoptry-Enriched Fractions from Cryptosporidium parvum

文献类型: 外文期刊

第一作者: Chen, Zhaoguo

作者: Chen, Zhaoguo

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关键词: Cryptosporidium parvum;Rhoptry;Liquid chromatography;Mass spectrometry;Protein domain analysis

期刊名称:IRANIAN JOURNAL OF PUBLIC HEALTH ( 影响因子:1.429; 五年影响因子:1.857 )

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收录情况: SCI

摘要: Background: Rhoptries are unique secretory/excretory organelles that are found exclusively in the Apicomplexa, and their contents are discharged at the time of invasion and are critical in the establishment of productive infection. Several rhoptry proteins have been identified in Toxoplasma gondii, Plasmodium falciparum and Neospora caninum and have been linked not only with the parasites' adhesion and invasion processes but also with their intracellular pathways. To date, only one Cryptosporidium parvum rhoptry protein candidate related to TgRON1 of T. gondii and PfASP of P. falciparum has been reported.

分类号: R19

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