Full-length genomic characterization and molecular evolution of canine parvovirus in China

文献类型： 外文期刊

第一作者： Zhou, Ling

作者： Zhou, Ling;Shi, Lijun;Liang, Lin;Cui, Shangjin;Tang, Qinghai;Mao, Qianqian;Bu, Bin;Yao, Lunguang;Kong, Miaomiao;Cui, Shangjin;Zhao, Kai;Leal, Elcio

作者机构：

关键词： CPV-2;Phylogenetic analysis;Viral evolution

期刊名称：VIRUS GENES （ 影响因子：2.332； 五年影响因子：2.0 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Canine parvovirus type 2 (CPV-2) can cause acute haemorrhagic enteritis in dogs and myocarditis in puppies. This disease has become one of the most serious infectious diseases of dogs. During 2014 in China, there were many cases of acute infectious diarrhoea in dogs. Some faecal samples were negative for the CPV-2 antigen based on a colloidal gold test strip but were positive based on PCR, and a viral strain was isolated from one such sample. The cytopathic effect on susceptible cells and the results of the immunoperoxidase monolayer assay, PCR, and sequencing indicated that the pathogen was CPV-2. The strain was named CPV-NY-14, and the full-length genome was sequenced and analysed. A maximum likelihood tree was constructed using the full-length genome and all available CPV-2 genomes. New strains have replaced the original strain in Taiwan and Italy, although the CPV-2a strain is still predominant there. However, CPV-2a still causes many cases of acute infectious diarrhoea in dogs in China.

分类号： R37

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