A new phenylethanoid glycoside from Orobanche cernua Loefling

文献类型： 外文期刊

第一作者： Qu, Zheng-yi

作者： Qu, Zheng-yi;Zhang, Yu-wei;Zheng, Si-wen;Yao, Chun-lin;Jin, Yin-ping;Zheng, Pei-he;Sun, Cheng-he;Wang, Ying-ping

作者机构：

关键词： Orobanchaceae;Orobanche cernua Loefling;phenylethanoid glycoside;cytotoxicity

期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）

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年卷期：

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收录情况： SCI

摘要： A novel phenylethanoid glycoside, 3-O-methyl isocrenatoside (1), along with two known compounds, methyl caffeate (2) and protocatechuic aldehyde (3), were isolated from the fresh whole plant of Orobanche cernua Loefling. All the isolated compounds (1-3) were elucidated on the basis of spectroscopic analysis including IR, MS and NMR data. The cytotoxic activities of these compounds were evaluated. Results showed that 3-O-methyl isocrenatoside (1) and methyl caffeate (2) exhibited significant cytotoxicity, with IC50 values of 71.89, 36.97g/mL and 32.32, 34.58g/mL against the B16F10 murine melanoma and Lewis lung carcinoma cell lines, respectively.

分类号： R9

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