Serotype, antigenicity, and pathogenicity of a naturally recombinant TW I genotype infectious bronchitis coronavirus in China

文献类型： 外文期刊

第一作者： Gao, Mengying

作者： Gao, Mengying;Wang, Qiuling;Zhao, Wenjun;Chen, Yuqiu;Zhang, Tingting;Han, Zongxi;Xu, Qianqian;Kong, Xiangang;Liu, Shengwang

作者机构：

关键词： Cystic oviduct;Infectious bronchitis coronavirus;Naturally recombinant TW I genotype;Nephritis;Serotype

期刊名称：VETERINARY MICROBIOLOGY （ 影响因子：3.293； 五年影响因子：3.599 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Since 2009, strains of the naturally recombinant TW I genotype of infectious bronchitis virus (IBV) have caused considerable damage to the Chinese poultry industry. To better understand the antigenicity and pathogenesis of this genotype, the characteristics of the ck/CH/LDL/140520 strain were compared to those of four commercial IB vaccine strains that are used commonly in China, as well as four attenuated viruses that represent two types of IBV strains, which are believed to have originated in China and are the predominant IBV types circulating in chicken flocks in China and many other parts of the world. The results showed that all eight strains were genetically and serotypically different from the strain ck/CH/LDL/140520. Furthermore, neither the vaccine strains nor the attenuated viruses could provide complete respiratory protection of chickens against a challenge with the ck/CH/LDL/140520 strain, indicating that it is necessary to develop new live vaccines or to evaluate the use of established vaccines in combination to control naturally recombinant TW I-type IBV strains in the future. Our results showed that strain ck/CH/LDL/140520 is very pathogenic, and that it is able to cause cystic oviductsin a high percentage of birds, as well as mortality due to nephritis and respiratory distress with complete tracheal ciliostasis, especially in chickens infected at 1 day of age. (C) 2016 Elsevier B.V. All rights reserved.

分类号： S8

  • 相关文献

[1]Identification and molecular characterization of a novel serotype infectious bronchitis virus (GI-28) in China. Chen, Yuqiu,Jiang, Lei,Zhao, Wenjun,Liu, Liangliang,Zhao, Yan,Shao, Yuhao,Li, Huixin,Han, Zongxi,Liu, Shengwang.

[2]Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China. Chen, Lingfeng,Zhang, Tingting,Han, Zongxi,Liang, Shuling,Xu, Yang,Xu, Qianqian,Chen, Yuqiu,Zhao, Yan,Shao, Yuhao,Li, Huixin,Wang, Kexiong,Kong, Xiangang,Liu, Shengwang.

[3]Genome characterization, antigenicity and pathogenicity of a novel infectious bronchitis virus type isolated from south China. Jiang, Lei,Zhao, Wenjun,Han, Zongxi,Chen, Yuqiu,Zhao, Yan,Sun, Junfeng,Li, Huixin,Shao, Yuhao,Liu, Liangliang,Liu, Shengwang.

[4]Genetic, antigenic, and pathogenic characteristics of avian infectious bronchitis viruses genotypically related to 793/B in China. Han, Zongxi,Zhao, Wenjun,Chen, Yuqiu,Xu, Qianqian,Sun, Junfeng,Zhang, Tingting,Zhao, Yan,Liang, Shuling,Gao, Mengying,Wang, Qiuling,Kong, Xiangang,Liu, Shengwang.

[5]Serotype shift of a 793/B genotype infectious bronchitis coronavirus by natural recombination. Zhang, Tingting,Han, Zongxi,Xu, Qianqian,Wang, Qiuling,Gao, Mengying,Wu, Wei,Shao, Yuhao,Li, Huixin,Kong, Xiangang,Liu, Shengwang.

[6]Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5 '-17 kb region of the genome. Han, Zongxi,Zhang, Tingting,Xu, Qianqian,Gao, Mengying,Chen, Yuqiu,Wang, Qiuling,Zhao, Yan,Shao, Yuhao,Li, Huixin,Kong, Xiangang,Liu, Shengwang.

[7]Distribution, serological and molecular characterization of Vibrio parahaemolyticus from shellfish in the eastern coast of China. Zhao, Feng,Zhou, De-qing,Cao, Hui-hui,Ma, Li-ping,Jiang, Yan-hua,Zhao, Feng. 2011

[8]Genotyping of Haemophilus Parasuis Isolated from Northwest China Using PCR-RFLP Based on the ompA Gene. Chu, Yue-Feng,Gao, Peng-Chen,Zhao, Ping,He, Yin,Zhang, Nian-Zhang,Liu, Yong-Sheng,Liu, Ji-Xing,Lu, Zhong-Xin.

[9]Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection. Sun, Junfeng,Han, Zongxi,Shao, Yuhao,Cao, Zhongzan,Kong, Xiangang,Liu, Shengwang.

[10]Identification of the avian infectious bronchitis coronaviruses with mutations in gene 3. Liu, Shengwang,Zhang, Qingxia,Chen, Jianfei,Han, Zongxi,Shao, Yuhao,Kong, Xiangang,Tong, Guangzhi. 2008

[11]Characterization of a recombinant coronavirus infectious bronchitis virus with distinct S1 subunits of spike and nucleocapsid genes and a 3 ' untranslated region. Liu, Xiaoli,Ma, Huijie,Xu, Qianqian,Sun, Nana,Han, Zongxi,Sun, Chuyang,Guo, Hongbo,Shao, Yuhao,Kong, Xiangang,Liu, Shengwang. 2013

作者其他论文 更多>>

微信小程序