Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

文献类型: 外文期刊

第一作者: Liu, Xin

作者: Liu, Xin;Zhang, Junsheng;Liu, Qiao;Tang, Guihua;Wang, Hongsheng;Yin, Sheng;Fan, Chengqi

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关键词: Sarcophyton elegans;cembranoids;antimigratory activity

期刊名称:MOLECULES ( 影响因子:4.411; 五年影响因子:4.587 )

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收录情况: SCI

摘要: Four new cembranoids, sarcophelegans A-D (1-4) and six known analogues (5-10) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were elucidated through detailed spectroscopic analysis, and the absolute configuration of 1 was confirmed by single-crystal X-ray diffraction. The antimigratory potential of compounds 1-10 were evaluated and compounds 2 and 6 were found to inhibit human breast tumor MDA-MB-231 cell migration at 10 mu M.

分类号: O62

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