Simultaneous determination of flupyradifurone and its two metabolites in fruits, vegetables, and grains by a modified quick, easy, cheap, effective, rugged, and safe method using ultra high performance liquid chromatography with tandem mass spectrometry
文献类型: 外文期刊
第一作者: Liu, Xingang
作者: Liu, Xingang;Wu, Xiaohu;Dong, Fengshou;Xu, Jun;Zheng, Yongquan
作者机构:
关键词: Flupyradifurone;Injection solvents;Metabolites;Tandem mass spectrometry;Ultra high performance liquid chromatography
期刊名称:JOURNAL OF SEPARATION SCIENCE ( 影响因子:3.645; 五年影响因子:2.943 )
ISSN:
年卷期:
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收录情况: SCI
摘要: An effective analytical method for the simultaneous determination of a novel insecticide flupyradifurone and its two metabolites was developed using ultra high performance liquid chromatography with tandem mass spectrometry coupled with a quick, easy, cheap, effective, rugged, and safe procedure. The three target compounds were extracted with acetonitrile and cleaned up with octadecylsilane, and were separated successfully between 1.9 and 3.1 min using an HSS T3 chromatographic column connected to an electrospray ionization source. All the matrix-matched samples at three fortified levels (0.01, 0.05, and 0.5 mg/kg) provided satisfactory recoveries in the range of 70.3-116.5% with relative standard deviations below 18.6%. The limits of quantitation were 10 g/kg for flupyradifurone and difluoroethylamino-furanone and 100 g/kg for 6-chloronicotinic acid. The limit of quantification of flupyradifurone was far below the maximum residue limit in the USA. The method is of great significance for establishing maximum residue limits in China.
分类号: O6
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