Effects of aluminum chloride on serum proteins, bilirubin, and hepatic trace elements in chickens

文献类型: 外文期刊

第一作者: Wang, Ben

作者: Wang, Ben;Zhang, Hongling;Liu, Liming;Li, Guojiang;Song, Yongli;Zhu, Yanzhu;Li, Yanfei

作者机构:

关键词: AI;liver;chickens;trace elements;protein;bilirubin

期刊名称:TOXICOLOGY AND INDUSTRIAL HEALTH ( 影响因子:2.273; 五年影响因子:2.257 )

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收录情况: SCI

摘要: The aim of this study was to reveal the effects of aluminum chloride (AlCl3) on the hepatic metabolism function and trace elements' distribution. Two hundred healthy male chickens ( I day old) were intraperitoneally administered with AlCl3 (0, 18.31, 27.47, and 36.62 mg kg(-1) day(-1) of Al3+) consecutively for 3 days. Then the chickens were allowed to rest for I day. The cycle lasted four days. The cycle was repeated 15 times (60 days). The contents of serum total protein (TP), albumin (ALB), total bilirubin (TBI), direct bilirubin (DBI), hepatic aluminum (Al), copper (Cu), iron (Fe), and zinc (Zn) were examined. The results showed that the contents of serum TP and ALB and hepatic Fe and Zn decreased and the contents of serum TBI and DBI and hepatic Al and Cu increased in the chickens with AlCl3. This indicates that chronic administration of AICl(3) impairs the hepatic metabolism function and disorders the hepatic trace elements' distribution.

分类号: R99

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