Genetics, Receptor Binding, and Virulence in Mice of H10N8 Influenza Viruses Isolated from Ducks and Chickens in Live Poultry Markets in China

文献类型: 外文期刊

第一作者: Deng, Guohua

作者: Deng, Guohua;Shi, Jianzhong;Wang, Jing;Kong, Huihui;Cui, Pengfei;Zhang, Fang;Tan, Dan;Liu, Liling;Jiang, Yongping;Guan, Yuntao;Chen, Hualan;Suzuki, Yasuo

作者机构:

期刊名称:JOURNAL OF VIROLOGY ( 影响因子:5.103; 五年影响因子:5.078 )

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收录情况: SCI

摘要: We analyzed eight H10N8 viruses isolated from ducks and chickens in live poultry markets from 2009 to 2013 in China. These viruses showed distinct genetic diversity and formed five genotypes: the four duck isolates formed four different genotypes, whereas the four chicken viruses belong to a single genotype. The viruses bound to both human-and avian-type receptors, and four of the viruses caused 12.7% to 22.5% body weight loss in mice.

分类号: Q934.2

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