Outbreak of severe pseudorabies virus infection in pig-offal-fed farmed mink in Liaoning Province, China

文献类型： 外文期刊

第一作者： Liu, Hao

作者： Liu, Hao;Li, Xin-Tong;Hu, Bo;Deng, Xiao-Yu;Zhang, Lei;Lian, Shi-Zhen;Zhang, Hai-Ling;Lv, Shuang;Xue, Xiang-Hong;Lu, Rong-Guang;Shi, Ning;Yan, Xi-Jun;Yan, Ming-Hao;Xiao, Peng-Peng

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期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）

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收录情况： SCI

摘要： An outbreak of severe pseudorabies virus (PRV) infection in farmed mink occurred in northern China in late 2014, causing significant economic losses in the local fur industry. Here, we report the first case of a PRV outbreak in mink in northeastern China, caused by feeding farmed mink with raw pork or organs contaminated by PRV. Mink infected with virulent PRV exhibited diarrhea, neurologic signs, and higher mortality, which can be misdiagnosed as highly pathogenic mink enteritis virus (MEV), canine distemper virus (CDV), and food poisoning. However, these were excluded as causative agents by PCR or bacteria isolation. The duration of disease was 3-7 days, and the mortality rate was 80-90%. PRV was characterized using indirect immunofluorescence assays (IFA) and electron microscopy (EM). Phylogenetic analysis based on full-length genome sequences and those of individual genes of this novel virus strain showed that it clustered in an independent branch with several other PRV isolates from China.

分类号： R37

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