Accumulation and Determination of Phenylethanolamine A Residue in Hair of Swine and Sheep

文献类型: 外文期刊

第一作者: Suo Decheng

作者: Suo Decheng;Wang Ruiguo;Wang Peilong;Zhao Genlong;Fan Yufei;Fan Xia;Li Yang;Su Xiaoou

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期刊名称:JOURNAL OF ANALYTICAL TOXICOLOGY ( 影响因子:3.367; 五年影响因子:3.21 )

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收录情况: SCI

摘要: The present study proposed the use of liquid chromatography-tandem mass spectrometry to detect the novel beta-agonist phenylethanolamine A (PEA) in incurred hair samples of swine and sheep and to assess its accumulation for residue monitoring. The method showed good percent recoveries ranging from 93.2% to 102% and good coefficient of variation at < 15%. The experiment was conducted in swine (24 treated and 4 controls) and sheep (3 treated and 1 control). PEA concentration was determined in hair during the treatment. High residue concentrations were present in hair as early as Day 24 (14.8 +/- 3.6 and 25.8 +/- 7.6 ng/g) and Day 21 (23.4 +/- 6.6 ng/g) for swine and sheep; these residues persisted until withdrawal on Days 14 and 21. Results showed high PEA accumulation in hair, thereby indicating the use of hair as a matrix in the control of PEA abuse in farm animals.

分类号: R99

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