Enantioseparation of Imazalil and Monitoring of Its Enantioselective Degradation in Apples and Soils Using Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry

文献类型： 外文期刊

第一作者： Li, Runan

作者： Li, Runan;Dong, Fengshou;Xu, Jun;Liu, Xingang;Wu, Xiaohu;Pan, Xinglu;Tao, Yan;Chen, Zenglong;Zheng, Yongquan

作者机构：

关键词： imazalil;enantioselectivity;apple;field soil;ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)

期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Imazalil is a widely used systemic chiral fungicide that is still being employed as a racemic mixture without distinguishing the difference between enantiomers, which often leads to its inaccurate risk assessment. In this study, a robust and highly sensitive chiral separation method was developed for imazalil enantiomers by ultrahigh-performance liquid chromatography tandem mass spectrometry and was further applied to study the degradation dynamics of imazalil enantiomers in apples and field soils at three sites in China. The baseline enantioseparation for imazalil was achieved within 3.5 min on a Lux Cellulose-2 (CCMPC) column with acetonitrile (ACN)/water (65:35, v/v) with a mobile phase at 0.5 mL/min flow rate and a column temperature of 20 degrees C. The limit of quantitation (LOQ) for each enantiomer was <0.60 mu g/kg, with a baseline resolution of approximately 1.75. The research showed that (S)-(+)-imazalil degraded more rapidly than (R)-(-)-imazalil in Gala apples, whereas (R)-()-imazalil preferentially degraded in Golden Delicious apples. No significant enantioselectivity was observed in OBIR-2T-47 apples and field soils from the three sites. Results of this study provide useful references for risk assessment and the rational use of imazalil in further agricultural produce practice.

分类号： R15`S

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