Molecular and immune response characterizations of a novel Bax inhibitor-1 gene in pufferfish, Takifugu obscurus

文献类型： 外文期刊

第一作者： Cheng, Chang-Hong

作者： Cheng, Chang-Hong;Guo, Zhi-Xun;Luo, Sheng-Wei;Wang, An-Li;Guo, Zhi-Xun

作者机构：

关键词： Takifugu obscurus;Bi-1;Gene expression;Immune responses;Apoptosis

期刊名称：FISH PHYSIOLOGY AND BIOCHEMISTRY （ 影响因子：2.794； 五年影响因子：2.876 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Apoptosis plays a crucial role in many biological processes, including development, cellular homeostasis, and immune responses. Bax inhibitor-1 (BI-1) is an anti-apoptotic protein that protects cells from endoplasmic reticulum stress-induced apoptosis. In this study, a BI-1 gene from the pufferfish Takifugu obscurus (Pf-BI-1) was identified and characterized. The full length of Pf-BI-1 cDNA was 1387 bp, including a 5'-UTR of 82 bp, a 3'-UTR of 591 bp containing a poly-(A) tail, and an open reading frame (ORF) of 714 bp that encodes a polypeptide of 237 amino acids. Pf-BI-1 was ubiquitously expressed in various tissues, with the highest expression levels in the blood, brain, and gill. The expression of Pf-BI-1 was up-regulated in a time-dependent manner after heat shock stress, ammonia stress, and bacterial challenge. Intracellular localization revealed that Pf-BI-1 was primarily localized in the cell cytoplasm. Furthermore, over-expression of Pf-BI-1 could active NF-kappa B reporter genes in HeLa cells. These results indicated that Pf-BI-1 may be involved in the apoptosis and immunity process against ambient stressors in pufferfish.

分类号： S85

  • 相关文献

[1]Immune and physiological responses of pufferfish (Takifugu obscurus) under cold stress. Cheng, Chang-Hong,Guo, Zhi-Xun,Ye, Chao-Xia,Wang, An-Li,Guo, Zhi-Xun.

[2]Effects of dietary resveratrol supplementation on hepatic and serum pro-/anti-inflammatory activity in juvenile GIFT tilapia, Oreochromis niloticus. Zheng, Yao,Wu, Wei,Song, Chao,Meng, Shunlong,Fan, Limin,Bing, Xuwen,Chen, Jiazhang,Zheng, Yao,Zhao, Zhixiang,Wu, Wei,Bing, Xuwen,Chen, Jiazhang.

[3]The p53-Bak apoptotic signaling axis plays an essential role in regulating differentiation of the ocular lens. Deng, M.,Ji, W.,Zhang, X.,Gong, L.,Hu, X.,Hu, W.,Xiao, L.,Li, D. W. -C.,Chen, P.,Liu, F.,Fu, S.,Tang, H.,Fu, Y.,Xiong, Z.,Hui, S.,Hu, X.,Hu, W.,Xiao, L.,Liu, W. -B.,Xiao, Y. -M.,Liu, S. -J.,Liu, Y.,Li, D. W. -C.,Zhang, L.,Sun, S.,Liu, J.,Li, D. W. -C..

[4]Comparison of the developmental competence and quality of bovine embryos obtained by in vitro fertilization with sex-sorted and unsorted semen from seven bulls. Liu, Xia,Hu, Tingxi,Sun, Weijun,Hao, Haisheng,Liu, Yan,Zhao, Xueming,Zhu, Huabin,Du, Weihua,Hu, Tingxi.

[5]Transcriptome analysis gene expression in the liver of Coilia nasus during the stress response. Du, Fukuan,Xu, Gangchun,Nie, Zhijuan,Xu, Pao,Gu, Ruobo. 2014

[6]BIRC7 gene in channel catfish (Ictalurus punctatus): Identification and expression analysis in response to Edwardsiella tarda, Streptococcus iniae and channel catfish Hemorrhage Reovirus. Li, Min,Wang, Qi-Long,Chen, Song-Lin,Sha, Zhen-Xia,Li, Min,Liu, Yang.

[7]The protective effects of vitamin C on apoptosis, DNA damage and proteome of pufferfish (Takifugu obscurus) under low temperature stress. Cheng, Chang-Hong,Liang, Hai-Yan,Luo, Sheng-Wei,Wang, An-Li,Ye, Chao-Xia. 2018

[8]Effects of high temperature on biochemical parameters, oxidative stress, DNA damage and apoptosis of pufferfish (Takifugu obscurus). Cheng, Chang-Hong,Guo, Zhi-Xun,Luo, Sheng-Wei,Wang, An-Li,Guo, Zhi-Xun. 2018

[9]Effect of dietary astaxanthin on the growth performance, non-specific immunity, and antioxidant capacity of pufferfish (Takifugu obscurus) under high temperature stress. Cheng, Chang-Hong,Guo, Zhi-Xun,Cheng, Chang-Hong,Guo, Zhi-Xun,Ye, Chao-Xia,Wang, An-Li,Ye, Chao-Xia,Wang, An-Li. 2018

[10]Isolation and characterization of polymorphic microsatellite loci from a dinucleotide-enriched genomic library of obscure puffer (Takifugu obscurus) and cross-species amplification. Ma, Hongyu,Chen, Songlin,Liao, Xiaolin,Xu, Tianjun,Ma, Hongyu,Ge, Jiachun.

[11]Transcriptome analysis reveals the potential mechanism of the albino skin development in pufferfish Takifugu obscurus. Jin, Wu,Wen, Haibo,Gu, Ruobo,Jin, Wu,Du, Xingwei,Zheng, Jinliang.

[12]Effects of dietary hawthorn extract on growth performance, immune responses, growth- and immune-related genes expression of juvenile golden pompano (Trachinotus ovatus) and its susceptibility to Vibrio harveyi infection. Tan, Xiaohong,Huang, Zhong,Zhou, Chuanpeng,Lin, Heizhao,Tan, Lianjie,Xun, Pengwei,Huang, Qian,Tan, Xiaohong,Sun, Zhenzhu,Huang, Zhong,Lin, Heizhao. 2017

[13]Evaluation of the Pathogenicity of a Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Variant in Piglets. Wei Tian-chao,Tian Zhi-jun,An Tong-qing,Jiang Yi-feng,Xiao Yan,Hu Shou-ping,Peng Jin-mei,Hao Xiao-fang,Zhang Shan-rui,Tong Guang-zhi,Zhou Yan-jun,Tong Guang-zhi,Wei Tian-chao. 2011

[14]Enhancement of mucosal immune responses by intranasal co-delivery of Newcastle disease vaccine plus CpG oligonucleotide in SPF chickens in vivo. Zhang, Linghua,Zhang, Meirong,Li, Jiaoqing,Cao, Ting,Tian, Xingshan,Zhou, Fengzhen. 2008

[15]Intranasal administration of CpG oligonucleotides induces mucosal and systemic Type 1 immune responses and adjuvant activity to porcine reproductive and respiratory syndrome killed virus vaccine in piglets in vivo. Zhang, Linghua,Tian, Xingshan,Zhou, Fengzhen. 2007

[16]A candidate RxLR effector from Plasmopara viticola can elicit immune responses in Nicotiana benthamiana. Li, Xinlong,Liu, Yunxiao,Zhang, Yali,Lu, Jiang,Xiang, Jiang,Lu, Jiang,Yin, Ling,Qu, Junjie,Lu, Jiang. 2017

[17]Pathological and immunological characteristics of piglets infected experimentally with a HP-PRRSV TJ strain. Li, Zhenguang,He, Yanliang,Li, Shufen,Xia, Mingqi,Wu, Hua,Li, Zhenguang,Leng, Xue,Wen, Yongjun,Wang, Fengxue,Cheng, Shipeng,Wu, Hua,Xu, Xiaoqin. 2016

[18]Molecular Characterization and Expression Analysis of Matrix Metalloproteinase 3 in the Asian Yellow Pond Turtle Mauremys mutica. Zhao, Mi,Shi, Yan,Zhao, Jian,Zhu, Xinping,Chen, Kunci,Pan, Debo,Wet, Chengqing. 2014

[19]Molecular Characterization and Expression Analysis of VSIG4 from the Asian Yellow Pond Turtle, Mauremys mutica. Zhao, Mi,Shi, Yan,Zhu, Xinping,Chen, Kunci,Pan, Debo,Wei, Chengqing. 2012

[20]Immune response and protection in gibel carp, Carassius gibelio, after vaccination with beta-propiolactone inactivated cyprinid herpesvirus 2. Zhang, Linlin,Gu, Zemao,Zeng, Lingbing,Zhang, Linlin,Ma, Jie,Fan, Yuding,Zhou, Yong,Xu, Jin,Liu, Wenzhi,Zeng, Lingbing.

作者其他论文 更多>>

微信小程序