Therapeutic Strategies of Plant-derived Compounds for Diabetes Via Regulation of Monocyte Chemoattractant Protein-1

文献类型: 外文期刊

第一作者: Czemplik, Magdalena

作者: Czemplik, Magdalena;Kulma, Anna;Szopa, Jan;Wang, Yu Fu;Szopa, Jan;Szopa, Jan

作者机构:

关键词: Diabetes;monocyte chemoattractant protein-1 (MCP-1);CCR2;plant extracts;plant metabolites

期刊名称:CURRENT MEDICINAL CHEMISTRY ( 影响因子:4.53; 五年影响因子:4.676 )

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年卷期:

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收录情况: SCI

摘要: Background: Monocyte chemoattractant protein-1 (MCP-1) is a member of the CC chemokine family that plays a key role in the inflammatory process. It has been broadly studied in the aspect of its role in obesity and diabetes related diseases. MCP-1 causes the infiltration of macrophages into obese adipose tissue via binding to the CCR2 receptor and is involved in the development of insulin resistance.

分类号: R9

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