文献类型： 外文期刊
第一作者： Gao, Shandian
作者： Gao, Shandian;Du, Junzheng;Tian, Zhancheng;Niu, Qingli;Zheng, Fuying;Huang, Dexuan;Kang, Biao;Luo, Jianxun;Liu, Guangyuan;Yin, Hong;Yin, Hong
作者机构：
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： In this study, we report the complete genome sequence of bovine ephemeral fever virus (BEFV) JT02L, which has been used in our laboratory, in mainland China, for more than a decade. The genome is 14941 nucleotide (nt), comprising a leader sequence of 50 nt, nucleoprotein (N) gene of 1328 nt, phosphoprotein (P) gene of 858 nt, matrix protein (M) gene of 691 nt, glycoprotein (G) gene of 1897 nt, non-structural glycoprotein (G(NS)) gene of 1785 nt, alpha 1 alpha 2 gene of 638 nt, beta gene of 460 nt, gamma gene of 400 nt, large multi-functional enzyme (L) gene of 6470 nt and a trailer sequence of 73 nt. Individual genes are separated by intergenic regions (IGRs) of 26, 44, 47, 51, 37, 39, 68 and -21 nt respectively. The overall organization is similar to an Australian BEFV isolate BB7721 but demonstrates some distinctive features including longer alpha 3 and beta open reading frames, intact termination/polyadenylation (TTP) sequence downstream of the beta open reading frame and a longer beta-gamma IGR integrated with a 38 nt AT-rich fragment. To our knowledge, this is the first report describing the complete genome of a BEFV strain of East Asian lineage, which may facilitate studies on genomic diversity among geographic strains of BEFV in China and the world.
分类号： R37
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