Paired box 7 (Pax7) gene: molecular characterisation, polymorphism and its association with growth performance in goose (Anser cygnoides)

文献类型： 外文期刊

第一作者： Wang, C.

作者： Wang, C.;Yang, Y. Z.;Liu, Y.;Gong, S. M.;Wang, H. Y.;He, D. Q.

作者机构：

关键词： Body weight;cloning;Pax7;SNPs;Zhedong-White goose

期刊名称：BRITISH POULTRY SCIENCE （ 影响因子：2.095； 五年影响因子：2.266 ）

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年卷期：

页码：

收录情况： SCI

摘要： 1. Paired box (Pax7) gene is a member of the paired box family and plays a critical role in animal growth and muscle development. However, the molecular characterisation of the goose Pax7 gene is unknown.2. The open-reading frame of goose Pax7 is composed of 1509bp, which encodes a protein of 503 amino acids and shares high homology with Pax7 of other birds.3. Ten single-nucleotide polymorphisms were identified in the genomic DNA sequence, 8 located in the intron region and two located in the exon region.4. Association analysis showed the C122T locus was significantly associated with the body weight of Zhedong-White geese in week 4, 6, 8, 10 and 12.5. It was concluded that the goose Pax7 gene may be an important candidate gene for goose growth traits and marker-assisted selection.

分类号： S8

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