Identification of bioactives from Astragalus chinensis L.f. and their antioxidant, anti-inflammatory and anti-proliferative effects
文献类型: 外文期刊
第一作者: Hu, Ting
作者: Hu, Ting;Hu, Ting;Liu, Qi-Mei;He, Xiao-Wei;Jiang, Jian-Guo;Huang, Fei;Zhang, Ming-Wei
作者机构:
关键词: Astragalus chinensis L.f.;Antioxidant;Antitumor;Anti-inflammatory;Formononetin;Calycosin
期刊名称:JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE ( 影响因子:2.701; 五年影响因子:3.574 )
ISSN:
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收录情况: SCI
摘要: This work was designed to obtain the valuable compounds with antioxidant, anti-proliferative and anti-inflammatory activities from Astragalus chinensis. Ethyl acetate fraction obtained from A. chinensis L.f. had significant antioxidant, anti-proliferative and anti-inflammatory activities. Subsequently, five single compounds were separated and purified, which were identified as formononetin (1), rhamnocitrin (2), calycosin (3), beta-daucosterol (4), rhamnocitrin-3-O-beta-d-glucoside (5). The results displayed that formononetin and rhamnocitrin exhibited significant cytotoxicity actions against tumor cell lines. Calycosin exerted the strongest anti-inflammatory effect of inhibition effects on NO production in macrophages.
分类号: TS2
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