Cumulative health risk assessment of co-occurring mycotoxins. of deoxynivalenol and its acetyl derivatives in wheat and maize: Case study, Shanghai, China
文献类型： 外文期刊
第一作者： Han, Zheng
作者： Han, Zheng;Nie, Dongxia;Yang, Xianli;Wang, Jianhua;Wu, Aibo;Han, Zheng;Ediage, Emmanuel Njumbe;De Saeger, Sarah;Chen, Bo;Li, Shuguang;On, Stephen L. W.
作者机构：
关键词： Co-occurring mycotoxins;Concentration addition concept;Cumulative risk assessment;Probabilistic analysis
期刊名称：FOOD AND CHEMICAL TOXICOLOGY （ 影响因子：6.023； 五年影响因子：5.844 ）
ISSN： 0278-6915
年卷期： 2014 年 74 卷
页码：
收录情况： SCI
摘要： Humans are naturally and frequently exposed to a multitude of mycotoxins, but health risk assessments are usually performed on individual mycotoxins, which may underestimate the total risks. In this study, we assessed for the first time the cumulative health risks of concomitant exposure via dietary intake (DI) to multiple mycotoxins, namely deoxynivalenol (DON) and its acetyl derivatives of 3-acetyldeoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), based on the concentration addition (CA) concept. A cross-sectional study was conducted in seven districts in Shanghai, China with 1269 participants and 330 wheat and maize samples analyzed. After probabilistic analysis using Monte Carlo simulation, the results showed no health risks to the population in Shanghai considering individual mycotoxins. However, if the cumulative health risks were calculated based on the combined consideration of DON with either 3-ADON or 15-ADON or both, the DI values in 95th percentile were up to 1087 ng/kg body weight/day, exceeding the Provisional Maximum Tolerable Daily Intake (PMTDI) of 1000 ng/kg body weight/day and hence representing potential health risks to the population in Shanghai. The integrated study proposed here could be a model strategy for cumulative health risk assessment on the co-occurring hazards in the fields of food safety combined with environmental contaminants. (C) 2014 Elsevier Ltd. All rights reserved.
分类号：
- 相关文献
作者其他论文 更多>>
-
Comparative Analysis of Prediction Models for Trawling Grounds of the Argentine Shortfin Squid Illex argentinus in the Southwest Atlantic High Seas Based on Vessel Position and Fishing Log Data
作者：Xiang, Delong;Sun, Yuyan;Zhu, Hanji;Wang, Jianhua;Huang, Sisi;Zhang, Shengmao;Zhang, Famou;Zhang, Heng;Xiang, Delong;Sun, Yuyan;Huang, Sisi;Zhang, Shengmao;Zhang, Famou;Zhang, Heng;Xiang, Delong;Sun, Yuyan;Huang, Sisi;Zhang, Shengmao;Zhang, Famou;Zhang, Heng;Zhu, Hanji;Wang, Jianhua
关键词：Southwest Atlantic;
Illex argentinus ; AIS; deep learning; fishing ground prediction -
A LTR retrotransposon insertion leads to leafy phenotype in maize by elevating ZmOM66 expression
作者：Du, Xuemei;Chen, Yan;Gao, Xinpeng;Wang, Xiaoli;Cui, Yu;Liu, Yunjun;Fu, Junjie;Wang, Guoying;Du, Xuemei;Xu, Zhuoyi;Lu, Jiawen;Zhang, Jie;He, Cheng;Huang, Liying;Guo, Wei;Cui, Yangbo;Ai, Junmin;Li, Li;Gu, Riliang;Wang, Jianhua
关键词：
-
2D/2D Co3O4/BiOCl nanocomposite with enhanced antibacterial activity under full spectrum: Synergism of mesoporous structure, photothermal effect and photocatalytic reactive oxygen species
作者：Wang, Xuesheng;Zhang, Zhijie;Shao, Yi;Yao, Chunxia;Huang, Liujuan;Song, Wei;Yang, Xianli
关键词：BiOCl; Photothermal effect; Antibacterial; Photocatalysis
-
Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for Staphylococcus aureus Infection Treatment
作者：Wu, Quanlong;Deng, Mengyin;Mao, Ruoyu;Yang, Na;Hao, Ya;Cao, Manli;Teng, Da;Wang, Jianhua;Wu, Quanlong;Deng, Mengyin;Mao, Ruoyu;Yang, Na;Hao, Ya;Cao, Manli;Teng, Da;Wang, Jianhua;Wu, Quanlong;Deng, Mengyin;Mao, Ruoyu;Yang, Na;Hao, Ya;Cao, Manli;Teng, Da;Wang, Jianhua
关键词：self-assembly gel; antimicrobial peptide;
Staphylococcus aureus ; mechanism; safety -
Occurrence of Co-Contamination and Interaction of Multi-Mycotoxins in Dairy Cow Feed in China
作者：Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Zhou, Xinli;Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Wang, Jianhua;Yang, Junhua;Ma, Junmei;Wang, Hongyang
关键词：feed; mycotoxin; co-contamination; correlation; interaction
-
Inhibitory Effect of Volatiles from Flavobacterium johnsoniae TR-18 on Aspergillus flavus Growth and Aflatoxin Production
作者：Gong, Andong;Liu, Jingrong;Wang, Gaozhan;Song, Mengge;Wang, Jianhua;Zhang, Jingbo
关键词：aflatoxins;
Aspergillus flavus ;Flavobacterium johnsoniae ; inhibition; volatiles -
Impact mechanisms of humic acid on the behavior of CMC-stabilized nZVI in groundwater: Implications for long-term chlorinated contaminant remediation
作者：Chen, Bo;Hang, Yuhan;Chen, Tianming;Chen, Bo;Cai, Shichao;Yang, Liwei;He, Feng;Chen, Bo;Cai, Shichao;Yang, Liwei;He, Feng;Chen, Bo;Cheng, Dong;Liang, Liyuan;Fan, Bo
关键词：Zero valent iron; Electron competition; Chlorinated hydrocarbons; Groundwater remediation; Natural organic matter
