Protective effect of retinoid against endotoxin-induced mastitis in rats

文献类型： 外文期刊

第一作者： Gu, B. -B.

作者： Gu, B. -B.;Miao, J. -F.;Deng, Y. -E.;Zou, S. -X.;Zhu, Y. -M.

作者机构：

关键词： Lipopolysaccharide;Mastitis;Retinoid;Rat

期刊名称：INFLAMMATION RESEARCH （ 影响因子：4.575； 五年影响因子：4.184 ）

ISSN： 1023-3830

年卷期： 2009 年 58 卷 2 期

页码：

收录情况： SCI

摘要： A lipopolysaccharide (LPS) induced mastitis model in rats was used to study the protective effect of retinoid. Commencing at gestation day 10, retinoid (dissolved in olive oil) or an equal volume of olive oil was administered to rats daily by gavage until parturition. LPS or pyrogen-free physiological saline was inoculated into the mammary gland 72h after parturition and the rats were euthanized at 12h post-infection. Myeloperoxidase (MPO), N-acetyl -beta-D- glucosaminidase (NAGase), tumor necrosis factor-alpha (TNF-alpha), interleukin-8 (IL-8) in mammary tissues and CD4(+)/CD8(+) in peripheral blood were increased and serum MPO and IL-2 in mammary tissues were decreased 12h after LPS infusion. Retinoid decreased MPO, NAGase, and TNF-alpha in mammary tissue and increased IL-2 in serum. Four thousand and 8000 I.U/kgaEuro cent d of retinoid significantly decreased the infiltration of PMNs in mammary alveoli and ameliorated the imbalance of CD4+/CD8+ in peripheral blood. These results suggest that retinoid protected against LPS-induced mastitis in a rat model.

分类号：

  • 相关文献

[1]Retinoid protects rats against neutrophil-induced oxidative stress in acute experimental mastitis. Gu, Beibei,Zhu, Wei,Miao, Jinfeng,Deng, Yu'E,Zou, Sixiang,Zhu, Yumin. 2009

[2]The effect of taurine on the toll-like receptors/nuclear factor kappa B (TLRs/NF-kappa B) signaling pathway in Streptococcus uberis-induced mastitis in rats. Miao, Jinfeng,Zheng, Liuhai,Ma, Zili,Zhu, Wei,Zou, Sixiang,Zhang, Jinqiu. 2011

[3]Taurine attenuates Streptococcus uberis-induced mastitis in rats by increasing T regulatory cells. Miao, Jinfeng,Zheng, Liuhai,Yu, Xiaoming,Zhu, Wei,Zou, Sixiang,Zhang, Jinqiu.

[4]Effects of sub-chronic aluminum chloride on spermatogenesis and testicular enzymatic activity in male rats. Zhu, Y. Z.,Fu, Yang,Wang, J.,Song, M.,Li, M.,Li, Y. F.,Zhu, Y. Z.,Miao, L. G.,Sun, H.. 2014

[5]Species differences for stereoselective metabolism of ethofumesate and its enantiomers in vitro. Zhu, W.,Dang, Z.,Liu, Y.,Lv, C.,Diao, J.,Zhou, Z.,Qiu, J.. 2009

[6]Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. Zhang, Jian-Xu,Zhang, Jin-Hua,Sun, Lixing,Feng, Zhi-Yong. 2008

[7]Inhibition of bone formation in rats by aluminum exposure via Wnt/beta-catenin pathway. Sun, Xudong,Wang, Haoran,Huang, Wanyue,Yu, Hongyan,Shen, Tongtong,Song, Miao,Han, Yanfei,Li, Yanfei,Zhu, Yanzhu.

[8]Effects of aluminum trichloride on the cartilage stimulatory growth factors in rats. Zhang, Fan,Yu, Hongyan,Yang, Xu,Song, Miao,Han, Yanfei,Li, Yanfei,Sun, Xudong,Zhu, Yanzhu.

[9]Protective effect of CpG-DNA against mastitis induced by Escherichia coli infection in a rat model. Zhu, Yumin,Fan, Hongjie,Miao, Jinfeng,Zou, Sixiang,Zhu, Yumin. 2008

[10]Comparative Proteomic Analysis Shows an Elevation of Mdh1 Associated with Hepatotoxicity Induced by Copper Nanoparticle in Rats. Dong Shu-wei,Gao Zhao-hui,Li Xia,Shen Xiao-yun,Gao Zhao-hui,Xue Hui-wen. 2014

[11]Effects of Fermentation Astragalus Polysaccharides on Experimental Hepatic Fibrosis. Qin, Zhe,Qin, Zhe,Li, Jianxi,Yang, Zhiqiang,Zhang, Kai,Zhang, Jinyan,Meng, Jiaren,Wang, Long,Wang, Lei. 2012

[12]UPLC-Q-TOF/MS-based urine and plasma metabonomics study on the ameliorative effects of aspirin eugenol ester in hyperlipidemia rats. Ma, Ning,Karam, Isam,Liu, Xi-Wang,Kong, Xiao-Jun,Qin, Zhe,Li, Shi-Hong,Jiao, Zeng-Hua,Dong, Peng-Cheng,Yang, Ya-Jun,Li, Jian-Yong.

[13]Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration. Li, Guanghui,Yang, Fan,He, Limin,Ding, Huanzhong,Sun, Na,Liu, Yingchun,Liu, Yiming,Shan, Qi,Li, Yafei,Zeng, Zhenling,Li, Guanghui,Yang, Fan,Liu, Yingchun,Liu, Yiming. 2012

[14]Hypolipidaemic effects of oat flakes and beta-glucans derived from four Chinese naked oat (Avena nuda) cultivars in Wistar-Lewis rats. Zhou, Xianrong,Lin, Weijing,Tong, Litao,Liu, Xingxun,Zhong, Kui,Liu, Liya,Wang, Lili,Zhou, Sumei.

[15]Sedative effects of Arachis hypogaea L. stem and leaf extracts on sleep-deprived rats. Zu, Xiaoyan,Xiong, Guangquan,Liao, Tao,Qiao, Yu,Geng, Shengrong,Li, Xin,Zhang, Zhenya,Li, Yiting. 2013

[16]Changes of cyclic AMP levels and phosphodiesterase activities in the rat ovary. Wang, Zhengchao,Shi, Fangxiong,Jiang, Yong-qing,LU, Li-zhi,Wang, Hao,Watanabe, Gen,Taya, Kazuyoshi. 2007

[17]Screening and characterization of lactic acid bacterial strains that produce fermented milk and reduce cholesterol levels. Guan, Xuefang,Xu, Qingxian,Zheng, Yi,Qian, Lei,Lin, Bin. 2017

[18]Regulation of FoxO1 transcription factor by nitric oxide and cyclic GMP in cultured rat granulosa cells (Retracted article. See vol 24, pg 281, 2007). Li, Xuebin,Jiang, Yongqing,Wang, Zhengchao,Liu, Gentao,Hutz, Reinhold J.,Liu, Wenbin,Xie, Zhuang,Shi, Fangxiong. 2005

[19]Aluminum trichloride impairs bone and downregulates Wnt/beta-catenin signaling pathway in young growing rats. Sun, Xudong,Cao, Zheng,Zhang, Qiuyue,Xu, Feibo,Che, Jianfang,Li, Yanfei,Pan, Chuanyi,Liang, Wannan,Liu, Shimin,Zhu, Yanzhu,Pan, Chuanyi,Liang, Wannan.

[20]Safety assessment of Maillard reaction products of chicken bone hydrolysate using Sprague-Dawley rats. Wang, Jin-Zhi,Sun, Hong-Mei,Zhang, Chun-Hui,Hu, Li,Li, Xia,Wu, Xiao-Wei. 2016

作者其他论文 更多>>

微信小程序